Results 91 to 100 of about 10,871,740 (304)

Robustness Measure of China’s Railway Network Topology Using Relative Entropy [PDF]

open access: yes, 2013
This study focused on China’s railway network topology issue from a robustness measure perspective. Relative entropy is used in the study as a measurement of robustness of railway network topology. It is found that the entropy-based measure provides more
Lei Wang, Fenling Feng
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A New Entropy Measure and COPRAS Method for Spherical Fuzzy Sets

open access: yesIEEE Access
One of the best ways to handle the ambiguity and unpredictable nature of decision-making is through fuzzy logic, and one of the most recent developments in this area is the concept of spherical fuzzy sets.
Abdul Haseeb Ganie   +2 more
doaj   +1 more source

New Fuzzy Entropy Measure of Order α

open access: yes, 2018
In this article, a new fuzzy entropy measure of order α is proposed. The fuzzy entropy axiomatic requirements are discussed for the new measure, and an empirical comparison are made with several entropy measures including Shannon, Rényi and Kapur.
Al-Talib, Mohammad, Al-Nasser, Amjad
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

An Overview of the Pathway Idea and Its Applications in Statistical and Physical Sciences

open access: yesAxioms, 2015
Pathway idea is a switching mechanism by which one can go from one functional form to another, and to yet another. It is shown that through a parameter α, called the pathway parameter, one can connect generalized type-1 beta family of densities ...
Nicy Sebastian   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Entropy Analysis and Neural Network-Based Adaptive Control of a Non-Equilibrium Four-Dimensional Chaotic System with Hidden Attractors

open access: yesEntropy, 2019
Today, four-dimensional chaotic systems are attracting considerable attention because of their special characteristics. This paper presents a non-equilibrium four-dimensional chaotic system with hidden attractors and investigates its dynamical behavior ...
Hadi Jahanshahi   +5 more
doaj   +1 more source

An entropy measure definition for finite interval-valued hesitant fuzzy sets

open access: yesKnowledge-Based Systems, 2015
In this work, a definition of entropy is studied in an interval-valued hesitant fuzzy environment, instead of the classical fuzzy logic or the interval-valued one.
Pelayo Quirós   +4 more
semanticscholar   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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