Results 71 to 80 of about 788,948 (294)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Sensors, 2015 Entropy in computer security is associated with the unpredictability of a source of randomness. The random source with high entropy tends to achieve a uniform distribution of random values.
Marcin Piotr Pawlowski +2 more
doaj +1 more source
Combinatorial Entropy for Distinguishable Entities in Indistinguishable States
, 2007 The combinatorial basis of entropy by Boltzmann can be written $H= {N}^{-1} \ln \mathbb{W}$, where $H$ is the dimensionless entropy of a system, per unit entity, $N$ is the number of entities and $\mathbb{W}$ is the number of ways in which a given ...
Andrea Rapisarda +5 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
How biased are maximum entropy models? [PDF]
, 2011 Maximum entropy models have become popular statistical models in neuroscience and other areas in biology, and can be useful tools for obtaining estimates of mutual information in biological systems.
Latham, Peter E. +2 more
core +3 more sources
Entropy production in systems with long range interactions
, 2017 On a fine grained scale the Gibbs entropy of an isolated system remains constant throughout its dynamical evolution. This is a consequence of Liouville's theorem for Hamiltonian systems and appears to contradict the second law of thermodynamics.
Levin, Yan, Pakter, Renato
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Advances in Mathematical PhysicsThis study presents a detailed numerical investigation of natural convection heat and mass transfer within a fluid-saturated porous quadrantal enclosure containing a heated circular cylinder and filled with TiO2–H2O nanoliquid.
Muhammad Jameel +3 more
doaj +1 more source
Entropy, 2015 This current work studies the heat transfer performance and entropy generation of natural convection in a nanofluid-filled U-shaped cavity. The flow behavior and heat transfer performance in the cavity are governed using the continuity equation, momentum
Ching-Chang Cho +3 more
doaj +1 more source
Numerical Study of Entropy Generation in a Vertical Square Channel Packed with Saturated Porous Media [PDF]
Engineering and Technology Journal, 2011 Entropy generation in a vertical square channel packed with saturated porous media, and subjected to differentially heated isothermal walls has been numerically investigated.
Abdulhassan A. Karamallah +2 more
doaj +1 more source