Results 71 to 80 of about 70,649 (267)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
A Lower Estimate for Entropy Numbers
Journal of Approximation Theory, 2001 The \(k\)-th entropy number \(e_k(T)\) of a bounded and linear operator \(T:X \to Y\) between quasi-Banach spaces \(X\) and \(Y\) is defined as the infimum of the \(\delta\)'s such that the image by \(T\) of the unit ball of \(X\) can be covered by \(2^{k-1}\) balls of radius \(\delta\) in \(Y\). For the case when \(T\) is the identity operator between
openaire +2 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Graph-Theoretic Limits of Distributed Computation: Entropy, Eigenvalues, and Chromatic Numbers
EntropyWe address the problem of the distributed computation of arbitrary functions of two correlated sources, X1 and X2, residing in two distributed source nodes, respectively.
Mohammad Reza Deylam Salehi, Derya Malak
doaj +1 more source
Entropy numbers, s-numbers, and eigenvalue problems
Journal of Functional Analysis, 1981 AbstractWe establish inequalities between entropy numbers and approximation numbers for operators acting between Banach spaces. Furthermore we derive inequalities between eigenvalues and entropy numbers for operators acting on a Banach space. The results are compared with the classical inequalities of Bernstein and Jackson.
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Entropy, 2018 Entropy generation in thermal convection with differentially discrete heat boundary conditions at various Rayleigh numbers (Ra) are numerically investigated using the lattice Boltzmann method.
Zhengdao Wang, Yikun Wei, Yuehong Qian
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source