Results 91 to 100 of about 265,948 (327)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Entropy current and entropy production in relativistic spin hydrodynamics

open access: yesPhysics Letters B
We use a first-principle quantum-statistical method to derive the expression of the entropy production rate in relativistic spin hydrodynamics. We show that the entropy current is not uniquely defined and can be changed by means of entropy-gauge ...
Francesco Becattini   +2 more
doaj   +1 more source

Analysis of entropy production in some enclosed subsystems where spontaneous processes take place [PDF]

open access: yesINCAS Bulletin, 2016
It is well-known that every spontaneous process occurring in an isolated system is accompanied by increasing entropy. The goal of this paper is to show that if the system is made of several subsystems, the entropy production of some subsystems can be ...
Marius BREBENEL
doaj   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Statistical properties of entropy production derived from fluctuation theorems

open access: yes, 2010
Several implications of well-known fluctuation theorems, on the statistical properties of the entropy production, are studied using various approaches. We begin by deriving a tight lower bound on the variance of the entropy production for a given mean of
Harris R J   +6 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Fluctuation Theorems of Brownian Particles Controlled by a Maxwell's Demon

open access: yes, 2006
We study the stochastic dynamics of Brownian particles in a heat bath and subject to an active feedback control by an external, Maxwell's demon-like agent.
E. Schrödinger   +3 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Equivalent definitions of the quantum nonadiabatic entropy production

open access: yes, 2014
The nonadiabatic entropy production is a useful tool for the thermodynamic analysis of continuously dissipating, nonequilibrium steady states. For open quantum systems, two seemingly distinct definitions for the nonadiabatic entropy production have ...
Horowitz, Jordan M., Sagawa, Takahiro
core   +1 more source

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