Results 61 to 70 of about 11,320,320 (289)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Dynamics of Entropy Production Rate in Two Coupled Bosonic Modes Interacting with a Thermal Reservoir

Entropy, 2022
The Markovian time evolution of the entropy production rate is studied as a measure of irreversibility generated in a bipartite quantum system consisting of two coupled bosonic modes immersed in a common thermal environment. The dynamics of the system is
Tatiana Mihaescu, Aurelian Isar
doaj   +1 more source

An Analysis of the Characteristics of Internal Flow Losses of Seawater Circulation Pumps in Nuclear Power Plants Based on the Entropy Production Theory

Energies
The seawater circulation pump represents the pump product with the largest flow rate within nuclear power plants. Its energy consumption accounts for a substantial portion of the energy consumed by nuclear power plants.
Yifan Zhi, Qian Huang, Haonan Su, Huairui Li, Huazheng Chen, Qidi Ke, Qiang Fu   +6 more
doaj   +1 more source

Study on performance and flow loss of reactor coolant pump with different laws of guide vane angle

Energy Science & Engineering, 2023
To study the influence of different laws of guide vane angle on the performance of reactor coolant pump (RCP), five models of RCP with different guide vane were designed, and the three‐dimensional numerical calculation was carried out.
Daoxing Ye, Fengli Zhai, Yimin Luo, Jinchen Wu, Junlin Chen, Xide Lai   +5 more
doaj   +1 more source

Entropy production in classical Yang-Mills theory from glasma initial conditions [PDF]

Physical Review D, 2013
We study the thermalization process in classical Yang-Mills (CYM) field theory starting from noisy glasma-like initial conditions by investigating the initial-value sensitivity of trajectories. Kunihiro et al. linked entropy generation to the Kolmogorov-Sinai entropy, which gives the entropy production rate in classical chaotic systems, calculated ...
Iida, Hideaki, Kunihiro, Teiji, Mueller, Berndt, Ohnishi, Akira, Schaefer, Andreas, Takahashi, Toru T.   +5 more
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Flow energy loss characteristics of ducted propeller using entropy production theory

Zhongguo Jianchuan Yanjiu, 2022
ObjectiveIn order to accurately locate the zone and size of flow energy loss during the operation of a ducted propeller, the flow energy loss characteristics are analyzed from the perspective of energy.MethodSteady ducted propeller simulations are ...
Ke SONG, Bangcheng YANG
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Entropy production in an energy balance Daisyworld model

, 2008
Daisyworld is a simple mathematical model of a planetary system that exhibits self-regulation due to the nature of feedback between life and its environment.
Dyke, J. G.
core   +1 more source