Results 71 to 80 of about 188,099 (285)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Analysis of Energy Loss Characteristics in an Axial-Flow Reactor Coolant Pump Based on Entropy Production Theory

open access: yesEnergies
As the critical component of a nuclear power plant (NPP), the reactor coolant pump (RCP) will suffer energy losses during operation, which can lead to a series of safety issues and adversely affect the efficiency and stability of the NPP.
Zhong Li   +4 more
doaj   +1 more source

Of entropy production by radiative processes in a conceptual climate model

open access: yesMeteorologische Zeitschrift, 2012
The problem of calculating the global entropy production of the climate system is revisited. In the first place, means to set forth the entropy production due to absorption and emission of electromagnetic radiation are recalled.
Joachim Pelkowski
doaj   +1 more source

The positive entropy production property for augmented nonlinear hyperbolic models

open access: yesComptes Rendus. Mathématique, 2022
Given a first-order nonlinear hyperbolic system of conservation laws endowed with a convex entropy-entropy flux pair, we consider the class of weak solutions containing shock waves depending upon some small scale parameters.
LeFloch, Philippe G., Tesdall, Allen M.
doaj   +1 more source

Thermodynamics and Kinetic Theory of Relativistic Gases in 2-D Cosmological Models [PDF]

open access: yes, 2002
A kinetic theory of relativistic gases in a two-dimensional space is developed in order to obtain the equilibrium distribution function and the expressions for the fields of energy per particle, pressure, entropy per particle and heat capacities in ...
A. Di Prisco   +17 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Physical Origins of Entropy Production, Free Energy Dissipation and their Mathematical Representations

open access: yes, 2009
A complete mathematical theory of nonequilibrium thermodynamics of stochastic systems in terms of master equations is presented. As generalizations of isothermal entropy and free energy, two functions of states play central roles: the Gibbs entropy $S ...
A. I. Khinchin   +12 more
core   +1 more source

Quantum Theory of Entropy Production

open access: yes, 2018
In this thesis we develop an approach to nonequilibrium quantum-statistical mechanics which is based on the consideration of the thermodynamic entropy as being a quantum observable with an associated hermitian operator and with its own equation of motion, from which the rate of entropy production can be studied.
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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