Results 241 to 250 of about 116,703 (295)

Representation learning enables robust single cell phenotyping in whole slide liquid biopsy imaging. [PDF]

Sci Rep
Naghdloo A, Tessone D, Nagaraju RM, Zhang B, Kang J, Li S, Oberai A, Hicks JB, Kuhn P.   +8 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Enumeration of Bacteria in Suspensions Using Time Domain Reflectometry. [PDF]

ACS Meas Sci Au
Hu H, Lu Y, Horton R, Ren T.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

On the grammar of restricted-range numeral systems. [PDF]

Philos Trans R Soc Lond B Biol Sci
Bowern C.
europepmc   +1 more source

Exhaustive enumeration of Kochen-Specker vector systems

, 2004
Mladen Pavičić, Jean‐Pierre Merlet, Norman D. Megill   +2 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Predictive accuracy of surgeon gestalt for adverse postoperative outcomes: systematic review. [PDF]

Br J Surg
Yang JJ, Mullan SJ, Rayhan TM, Sandhu CKSS, Ramaiya AN, Heneghan CJ.   +5 more
europepmc   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Inflammatory Markers in Gastric Fluids Differentiate Patients With Eosinophilic Gastritis: Search for a Disease Screener. [PDF]

Clin Transl Gastroenterol
Pyne AL, Schuman SS, Brintz BJ, Dodds W, Silon B, Pletneva MA, Peterson KA.   +6 more
europepmc   +1 more source