Results 51 to 60 of about 4,160,774 (255)

Adjuvant-Mediated Epitope Specificity and Enhanced Neutralizing Activity of Antibodies Targeting Dengue Virus Envelope Protein

Frontiers in Immunology, 2017
The heat-labile toxins (LT) produced by enterotoxigenic Escherichia coli display adjuvant effects to coadministered antigens, leading to enhanced production of serum antibodies.
Denicar Lina Nascimento Fabris Maeda, Milene Tavares Batista, Milene Tavares Batista, Lennon Ramos Pereira, Mariana de Jesus Cintra, Jaime Henrique Amorim, Camila Mathias-Santos, Sara Araújo Pereira, Silvia Beatriz Boscardin, Sandriana dos Ramos Silva, Eliana L. Faquim-Mauro, Vanessa Barbosa Silveira, Danielle Bruna Leal Oliveira, Stephen Albert Johnston, Luís Carlos de Souza Ferreira, Juliana Falcão Rodrigues   +15 more
doaj   +1 more source

Transcription of the Envelope Protein by 1-L Protein–RNA Recognition Code Leads to Genes/Proteins That Are Relevant to the SARS-CoV-2 Life Cycle and Pathogenesis

Current Issues in Molecular Biology, 2022
The theoretical protein–RNA recognition code was used in this study to research the compatibility of the SARS-CoV-2 envelope protein (E) with mRNAs in the human transcriptome.
Jozef Nahalka
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins

Frontiers in Microbiology, 2022
The C-terminus of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein E contains a PBM (PDZ-binding motif) targeting PDZ (PSD-95/Dlg/ZO-1) domains, which is identical to the PBM of SARS-CoV.
Yanlei Zhu, Flavio Alvarez, Nicolas Wolff, Ariel Mechaly, Sébastien Brûlé, Benoit Neitthoffer, Sandrine Etienne-Manneville, Ahmed Haouz, Batiste Boëda, Célia Caillet-Saguy   +9 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Murine leukemia virus (MLV) replication monitored with fluorescent proteins [PDF]

, 2004
Background Cancer gene therapy will benefit from vectors that are able to replicate in tumor tissue and cause a bystander effect. Replication-competent murine leukemia virus (MLV) has been described to have potential as cancer therapeutics, however, MLV ...
Schnierle Barbara S, Sliva Katja, Erlwein Otto, Bittner Alexandra, Erlwein, Otto, Bittner, Alexandra, Sliva, Katja, Schnierle, Barbara   +7 more
core   +2 more sources

Interference of the Zika Virus E-Protein With the Membrane Attack Complex of the Complement System

Frontiers in Immunology, 2020
The complement system has developed different strategies to clear infections by several effector mechanisms, such as opsonization, which supports phagocytosis, attracting immune cells by C3 and C5 cleavage products, or direct killing of pathogens by the ...
Zahra Malekshahi, Britta Schiela, Sarah Bernklau, Zoltan Banki, Reinhard Würzner, Heribert Stoiber   +5 more
doaj   +1 more source

Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery [PDF]

, 2013
BACKGROUND: Different cell types have distinctive patterns of chromosome positioning in the nucleus. Although ectopic affinity-tethering of specific loci can be used to relocate chromosomes to the nuclear periphery, endogenous nuclear envelope proteins ...
Vassiliki Lazou, Harrison, David J, Schirmer, Eric C, David J Harrison, Zuleger, Nikolaj, de Las Heras, Jose I, Wendy A Bickmore, Dzmitry G Batrakou, Lazou, Vassiliki, Batrakou, Dzmitry G, Jose I de las Heras, Bickmore, Wendy A, Nikolaj Zuleger, Shelagh Boyle, Kelly, David A, Korfali, Nadia, Nadia Korfali, Glenn E Morris, Eric C Schirmer, Boyle, Shelagh, David A Kelly, K Natalie Randles, Randles, K Natalie, Morris, Glenn E, Harrison, David J; id_orcid   +24 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Immunization With Fc-Based Recombinant Epstein–Barr Virus gp350 Elicits Potent Neutralizing Humoral Immune Response in a BALB/c Mice Model

Frontiers in Immunology, 2018
Epstein–Barr virus (EBV) was the first human virus proved to be closely associated with tumor development, such as lymphoma, nasopharyngeal carcinoma, and EBV-associated gastric carcinoma. Despite many efforts to develop prophylactic vaccines against EBV
Bingchun Zhao, Xiao Zhang, Claude Krummenacher, Claude Krummenacher, Shuo Song, Shuo Song, Ling Gao, Haojiong Zhang, Miao Xu, Lin Feng, Qisheng Feng, Musheng Zeng, Yuting Xu, Yixin Zeng   +13 more
doaj   +1 more source