Results 31 to 40 of about 24,863 (225)

Protein and peptide profiles of rats’ organs in scorpion envenomation [PDF]

, 2023
Problem of scorpion envenomation becomes more alarming each year. Main effects of scorpion venom are commonly believed to be related to its neurotoxic properties, yet severe symptoms may also be developed due to the uncontrolled enzymatic activity and ...
Maievskyi, O., Raksha, N., Oleksandr Maievskyi, Oleksiy Savchuk, Gunas, I., Tetiana Vovk, Igor Gunas, Serhii Shchypanskyi, Vovk, T., Shchypanskyi, S., Nataliia Raksha, Savchuk, O., Valery Gunas, Gunas, V.   +13 more
core   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Scorpion envenomation-associated myocarditis: A systematic review.

, 2023
BackgroundScorpion envenomation is associated with several complications. One of the most serious complications is the cardiac involvement in the form of myocarditis that remains the main reason for mortalities associated with scorpion envenomation.
Mabrouk Bahloul, Amirhossein Roshanshad, Seyyed Hamidreza Ayatizadeh, Saeedreza Shirzadi, Seyed Alireza Zomorodian, Ali Ardekani, Amirali Tavangar, Reza Fereidooni   +7 more
core   +1 more source

A sensory ecology approach to understanding snakebites: Influence of sensory cues on the strike of the lancehead pitviper

Journal of Zoology, EarlyView.
Snakes are notable for having a broad range of predators and one of the most diverse repertoires of defensive behaviors. During heightened responses to aversive stimuli, one of the behaviors displayed is the venomous bite, particularly relevant because it triggers snakebite incidents in humans.
J. M. Alves‐Nunes, A. Fellone, R. H. Willemart, O. A. V. Marques   +3 more
wiley   +1 more source

Contribution to the distribution of spiders with significant medical importance (Araneae: Loxosceles and Latrodectus) in Iran, with a new record for the country [PDF]

Iranian Journal of Animal Biosystematics, 2014
A faunistic review is given on the Iranian medically important spiders of two genera Loxosceles and Latrodectus. Latrodectus cinctus Blackwall, 1865 is reported for the first time from Iran (and for the second time from Asia) and is replaced with the ...
Alireza Zamani, Omid Mirshamsi, Alireza Savoji, Mehran Shahi   +3 more
doaj   +1 more source

Clinical profile and outcome of AKI in snake bite in a tertiary care hospital, India

MAMC Journal of Medical Sciences, 2023
Introduction: Acute kidney injury (AKI) is one of the complications of envenomation that is frequently fatal. Aim: To evaluate the clinical profile and outcome of AKI in snake bite patients and to identify the predictors of mortality in these patients ...
Aruna Acharya, Haladhar Naik
doaj   +1 more source

Inflammation induced by snake venoms optimizes envenomation

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustrating mechanisms underlying direct vascular absorption and subsequent movement of venom toxins into the tissues consequent to snakebite. A, snakebite into prey deposits venom toxins into the tissue interstitium, with the venom then causing acute inflammation primarily in venules.
Dirk F. van Helden, Neil Spratt, Peter J. Dosen, Sally A. McFadden, John Holdsworth, Daniel J Beard, Kirsten Coupland, Phillip Jobling, Todd A. Hardy, Derek R. Laver   +9 more
wiley   +1 more source

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 7, Page 1403-1426, July 2026.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

The failures of ethnobotany and phytomedicine in delivering novel treatments for snakebite envenomation

, 2020
Snakebite envenomation (SBE) is a high priority, neglected tropical disease. This devastating occupational health hazard disproportionately affects rural farming communities in tropical countries.
Vaiyapuri, S., Williams, H. F., Trim, S., Trim, C.   +3 more
core   +1 more source