Results 101 to 110 of about 1,232,449 (309)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Environmental Assessment--FY 1979 Winter Navigation Demonstration on the St. Lawrence River--Technical Reports: Volume II; TR-N. Habitat Mapping and Critical Habitat Studies.

, 2010
Volume Two of the Environmental Assessment of the proposed FY 1979 Winter Navigation Demonstration on the St. Lawrence River.Although the shoreline littoral area is limited in extent, its significance is high, since resident fish populations have few ...
New York (State). Dept. of Environmental Conservation, SUNY College of Environmental Science and Forestry
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Life cycle assessment as an analytical tool in strategic environmental assessment. Lessons learned from a case study on municipal energy planning in Sweden

, 2012
Life cycle assessment (LCA) is explored as an analytical tool in strategic environmental assessment (SEA), illustrated by case where a previously developed SEA process was applied to municipal energy planning in Sweden.
Anna Björklund, Björklund, Anna,
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Environmental Impact Assessment follow-up: good practice and future directions – findings from a workshop at the IAIA 2000 conference

, 2001
Environmental impact assessment (EIA) follow-up refers to the activities undertaken during the post-decision stages of the process to monitor, evaluate, manage and communicate the environmental outcomes that occur in order to provide for some follow-up ...
Arts, J., Caldwell, P., Morrison-Saunders, A.   +2 more
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Methane emissions from riverine ecosystems in the Yangtze River basin are driven by ebullition rather than diffusion

Communications Earth & Environment
Quantifying methane emissions from riverine ecosystems is crucial for optimizing greenhouse gas control strategies. However, partitioning methane emissions between diffusion and ebullition pathways remains insufficiently investigated.
Xiuyuan Chen, Fuhong Sun, Jiayue Li, Ziteng Wang, Yiding Guo, Nannan Huang, Qianyu Zhao, Fengchang Wu   +7 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Codon usage bias is presumably affected by tRNA selection effects in Actinidia polyploidization events

BMC Genomics
Background Polyploidization is one of the main mechanisms in speciation, yet its effects on the frequency and distribution of synonymous codons remain unclear, which may lead to distinct patterns of codon usage bias (CUB) in polyploid species.
Yi Zhou, Zhilu Sheng, Dongbin Li, Wencui Li, Yujia Peng, Zhaopeng Song, Zhanjun Quan, Yongbo Liu   +7 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Environmental Assessment--FY 1979 Winter Navigation Demonstration on the St. Lawrence River--Technical Reports: Volume II; TR-L. Aquatic Food Web Characterization Studies.

, 2010
Volume Two of the Environmental Assessment of the proposed FY 1979 Winter Navigation Demonstration on the St. Lawrence River.Data gathered were reviewed and utilized to generate a preliminary concept of the aquatic ecosystem of the St. Lawrence River. A
New York (State). Dept. of Environmental Conservation, SUNY College of Environmental Science and Forestry
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