Results 51 to 60 of about 9,510,332 (304)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A review of literature and computer models on exposure assessment [PDF]

, 2009
At the present time, risk analysis is an effective management tool used by environmental managers to protect the environment from inevitable anthropogenic activities.
Oduyemi, K. O. K., Clark, M., Butt, Talib E., Coulon, F., Oduyemi, K, Coulon, Frederic, Oduyemi, K.O.K., Clark, Michael, Butt, T.E., Butt, T. E., Butt, Talib, Coulon, F   +11 more
core   +1 more source

What makes policy for wind- and solar energy on land acceptable? An assessment of perceived policy legitimacy

Humanities & Social Sciences Communications
Large-scale changes in society are required to achieve policy goals for a transition to a sustainable energy system. Understanding how citizens perceive regional plans for the placement of wind and solar can help policymakers design their policy. Our aim
Astrid L. Martens, Jarry T. Porsius, Kees Vringer   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Environmental Assessment of the Raritan Confluence Reservoir Force Main

, 1977
This document is an environmental assessment of the feasibility of six alignments to convey water from Round Valley to (and from) the confluence of the North and South Branches of the Raritan River.

core   +1 more source

Distribution of trace and toxic element monitoring in soil samples from the lesser Himalayan region of India, pollution indices and source identification

Discover Environment
Monitoring toxic and trace elements in soil is vital for environmental protection, agricultural productivity, and regulatory compliance, yet tailored methodologies for comprehensive soil analysis are limited, particularly in ecologically sensitive ...
Mahesh Tiwari, Tejas Rathod, Sanjay Kumar Sahu, Rahul Bhangare, Ajmal Yousuf, Vandana Pulhani   +5 more
doaj   +1 more source

An environmental health vocabulary and its semi-automated curation workflow

Evidence-Based Toxicology
The environmental health vocabulary (EHV) represents manually curated terminologies developed by the US Environmental Protection Agency’s (EPA) Chemical Pollutant Assessment Division (CPAD) for standardizing reporting of health effect information ...
Michelle Angrish, Scott Burns, Joshua Cleland, Caroline Foster, Samuel Kovach, Kristan Markey, Brittany Schulz, Andy Shapiro, Michele Taylor, George Woodall, Sean Watford   +10 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source