Results 121 to 130 of about 359,187 (310)

Chemometrics in Environmental Chemistry-Statistical Methods [PDF]

, 1996

openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The 2015 Annual Meeting of SETAC German Language Branch in Zurich (7-10 September, 2015): Ecotoxicology and environmental chemistry-from research to application. [PDF]

Environ Sci Eur, 2016
Werner I, Aldrich A, Becker B, Becker D, Brinkmann M, Burkhardt M, Caspers N, Campiche S, Chèvre N, Düring RA, Escher BI, Fischer F, Giebner S, Heye K, Hollert H, Junghans M, Kienle C, Knauer K, Korkaric M, Märkl V, Muncke J, Oehlmann J, Reifferscheid G, Rensch D, Schäffer A, Schiwy S, Schwarz S, Segner H, Simon E, Triebskorn R, Vermeirssen EL, Wintgens T, Zennegg M.   +32 more
europepmc   +1 more source

Special Articles: Environmental Sciences and Analytical Chemistry. Collection and determination of polycyclic aromatic hydrocarbons in air using XAD-2 resin adsorbent.

, 1994
Masaharu Murata, Mizuo Maeda, Minoru Koga, Toshiro YAMASHITA, Kimiko Haraguchi, Makoto Takagi   +5 more
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Recent advances in quantitative LA-ICP-MS analysis: challenges and solutions in the life sciences and environmental chemistry. [PDF]

Anal Bioanal Chem, 2015
Limbeck A, Galler P, Bonta M, Bauer G, Nischkauer W, Vanhaecke F.   +5 more
europepmc   +1 more source

THE ENVIRONMENTAL CHEMISTRY AND TOXICOLOGY OF SILVER [PDF]

, 1999
Anders Andrén, David E. Armstrong
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Special Articles: Environmental Sciences and Analytical Chemistry. Sensitive determination of humic acid in natural water by chemiluminescence-flow injection method.

, 1994
Xincheng Hu, Masaru Kitano, Norimichi Takenaka, Hiroshi Bandow, Yasuaki Maeda, Danian Zhang   +5 more
openalex   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source