Monitoring of PCDD/Fs and PCBs in European Eels (<i>Anguilla anguilla</i>) from Lake Garda: A Persistent Environmental Concern. [PDF]
Gallocchio F +12 more
europepmc +1 more source
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
A Bilingual Dataset for Testing Web Probing in the US and India: The Example of Measures of Environmental Concern. [PDF]
Arts I, van de Schoot R, Meitinger K.
europepmc +1 more source
Does having children increase environmental concern? Testing parenthood effects with longitudinal data from the New Zealand Attitudes and Values Study. [PDF]
Milfont TL, Poortinga W, Sibley CG.
europepmc +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Divergent effects of environmental concern and risk perception on pro-environmental intention: an international study across 17 countries. [PDF]
Kikko Y, Ishigaki T.
europepmc +1 more source
The Quality of Stakeholder-Based Decisions: Lessons from the Case Study Record [PDF]
The increased use of stakeholder processes in environmental decisionmaking has raised concerns that the inherently “political” nature of such processes may sacrifice substantive quality for political expediency.
Beierle, Thomas
core
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Enhancing groundwater vulnerability assessment for improved environmental management: addressing a critical environmental concern. [PDF]
Abduljaleel Y +7 more
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source

