Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Citation: 'environmental damage' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15667 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
ADDITIVE VERSUS PROPORTIONAL PEST DAMAGE FUNCTIONS: WHY ECOLOGY MATTERS [PDF]
Economic analyses of pests typically assume damage is either additively separable from pest free yield or proportional to it. This paper describes the ecological assumptions required for additive and proportional damage functions to demonstrate that both
Mitchell, Paul D.
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Examining host-State counterclaims for environmental damage in investor-State dispute settlement from human rights and transnational public policy perspectives. [PDF]
Int Environ Agreem, 2021 Gleason T.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Ecological and Economic Indicators of Oil and Gas Companies Functioning
Vestnik MGIMO-Universiteta, 2016 This article analyzes the basic ecological-economic indicators of oil and gas companies, in particular the various volumes of oil, the number of spills per year of CO2 emissions, the costs of environmental protection.
Anastasia V. Sheveleva
doaj
Crime of ecocide in Ukraine – environmental consequences of Russian military aggression
Studia Prawnicze KULEven though the definition of the crime of ecocide was proposed by the Independent Expert Panel in 2021 it has not been incorporated into any international agreement yet.
Ihor Kozak
doaj +1 more source
Testimony of Rena Steinzor…before the U.S. House of Representatives, Energy and Commerce Committee, Subcommittee on Environment and Economics. 112th Congress, 1st Session (2011). [PDF]
, 2011 Environmental regulations have saved millions of lives, preventing chronic respiratory illness and heart attacks in cities across the country. These rules protect children from irreversible neurological damage, save billions of dollars in cleanup costs ...
Steinzor, Rena I.
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source