Results 121 to 130 of about 13,473,267 (315)

DEVELOPMENT OF THE ASSESSMENT OF ENVIRONMENTAL DAMAGE AND ENVIRONMENTAL RISKS IN CASE OF ACCIDENTS WITH OIL ON RAILWAY TRANSPORT

Nauka ta progres transportu, 2010
The principles of estimation of losses to the environment components caused by the emergency spills of petroleum products and the methodical approaches to estimation of ecological risk of functioning of railways are offered.
Yu. V. Zelenko
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

THE INSTITUTION OF LIABILITY FOR ENVIRONMENTALOFFENSES: SYSTEMIC DEFICIENCIES AND JUDICIAL PRACTICE

Правовое государство: теория и практика
The complex nature of the institution of liability for environmental offenses is determined by the sectoral affiliation of the norms governing such relations.
NIKISHIN Vladislav Vasilievich
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

PROBLEM ISSUES OF ACCOUNTING AND VALUATION OF ENVIRONMENTAL DAMAGE

Вестник университета, 2019
The article discusses the role of accounting information, the basic organizational and functional issues accounting and valuation of environmental damage with the implementation of the principle of payment for the exploitation of the natural wealth of ...
T. Rogulenko
doaj  

Coal-exit health and environmental damage reductions outweigh economic impacts

Nature Climate Change, 2020
Sebastian Rauner, N. Bauer, A. Dirnaichner, R. Dingenen, C. Mutel, Gunnar Luderer   +5 more
semanticscholar   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

ANÁLISIS DOGMÁTICO DEL DERECHO PENAL AMBIENTAL CHILENO, A LA LUZ DEL DERECHO COMPARADO Y LAS OBLIGACIONES CONTRAÍDAS POR CHILE EN EL ÁMBITO DEL DERECHO INTERNACIONAL: CONCLUSIONES Y PROPUESTA LEGISLATIVA FUNDADA PARA UNA NUEVA PROTECCIÓN PENAL DEL MEDIO AMBIENTE EN CHILE

Ius et Praxis, 2003
El presente artículo corresponde al Informe Final del Proyecto FONDECYT 1010206­2001, sobre tratamiento penal de los delitos contra el medio ambiente en Chile.
Jean Pierre Matus Acuña, Marcos Orellana Cruz, Marcelo Castillo Sánchez, M Cecilia Ramírez Guzmán   +3 more
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source