Results 131 to 140 of about 1,410,058 (263)

Adaptation, internalization and environmental damage [PDF]

open access: yes, 2002
Existing literature ignores adaptation responses to external effects which, in turn, affect the design of appropriate internalization instruments.
Abrego, Lisandro, Whalley, John
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Ictiofauna do ribeirão Diamante, Estação Ecológica do Caiuá (Diamante do Norte, Estado do Paraná): monitoramento de sua composição e estrutura = Ichthyofauna of the Diamante stream, Caiuá Ecological Station (Diamante do Norte, Paraná State): monitoring its composition and structure

open access: yesActa Scientiarum: Biological Sciences, 2009
O objetivo do presente trabalho foi investigar as assembleias de peixes do ribeirão Diamante (Estação Ecológica do Caiuá), visando avaliar sua composição e estrutura, ao longo de dois períodos distintos: três e 11 anos após sua criação.
Bruno Ferezim Morales   +2 more
doaj  

The Environment - A Crucial Component of Long-Lived Upsurge in the European Union [PDF]

open access: yes
Environmental Community Policy aims at upholding long-lived development and at preserving the natural setting intact to the very benefit of both the extant and the yet unborn generations.
Victor Ionescu
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Back of the envelope estimates of environmental damage costs in Mexico [PDF]

open access: yes
For developing countries, budget constraints help set the agenda on mitigating environmental damage, one of the indelible marks of our era. Political considerations often dictate the measures taken.
Margulis, Sergio
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Delegation and emission tax in a differentiated oligopoly [PDF]

open access: yes
This paper examines how product differentiation as well as strategic managerial delegation affects optimal emission tax rate, environmental damage and social welfare, under alternative modes of product market competition. It shows that, under pure profit
Rupayan Pal
core   +3 more sources

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