Results 71 to 80 of about 9,055,161 (340)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Innovations in chemical degradation technologies for the removal of micro/nano-plastics in water: A comprehensive review

open access: yesEcotoxicology and Environmental Safety
Micro/nanoplastics (M/NPs) in water have raised global concern due to their potential environmental risks. To reestablish a M/NPs free world, enormous attempts have been made toward employing chemical technologies for their removal in water.
Saisai Guo   +4 more
doaj   +1 more source

Facile and Selective Synthesis of 2-Substituted Benzimidazoles Catalyzed by FeCl3/ Al2O3

open access: yesE-Journal of Chemistry, 2012
2-Substituted benzimidazoles were synthesized in a single pot from aromatic aldehydes and o-phenylenediamine catalyzed by FeCl3/ Al2O3 in DMF at ambient temperature attained good yields and high selectivity.
Guo-Feng Chen, Xiao-Yun Dong
doaj   +1 more source

Amphiphilic Cationic Peptide-Coated PHA Nanosphere as an Efficient Vector for Multiple-Drug Delivery

open access: yesNanomaterials, 2022
Amphiphilic core–shell (ACS) nanoparticles are gaining increasing research interest for multi-drug delivery in cancer therapy. In this work, a new cationic peptide-coated PHA nanosphere was prepared by self-assembly of a hydrophobic core of biodegradable
Fanghua Zhang   +7 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Reducing Energy Penalty in Wastewater Treatment: Fe-Cu-Modified MWCNT Electrodes for Low-Voltage Electrofiltration of OMC

open access: yesEnergies
Pseudo-persistent organic pollutants, such as pharmaceuticals, personal care products (PPCPs), and organic dyes, are a major issue in current environmental engineering.
Lu Yu   +4 more
doaj   +1 more source

One-Pot Synthesis of Some New Pyrido[2,3-d]pyrimidine Derivatives Catalyzed by Sodium Lauryl Sulfate in Aqueous Media

open access: yesE-Journal of Chemistry, 2010
A series of pyrido[2,3-d]pyrimidine derivatives were synthesized by the three-component reaction of aromatic aldehyde, malononitrile and 6-amino-4-hydroxy-2-mercaptopyrimidine catalyzed by sodium lauryl sulfate (SDS) in aqueous media.
Sheng-Hui Li   +3 more
doaj   +1 more source

Aggregation‐induced emission of copper nanoclusters

open access: yesAggregate, 2021
Copper nanoclusters (Cu NCs) have recently emerged as promising luminophores, featuring ultra‐small size, reasonable photostability, large Stokes shift, and long emission lifetimes.
Yu‐e Shi   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Biospectroscopy diagnosis of bacterial interaction with environmental molecules [PDF]

open access: yes, 2018
Aims: Bacteria are universal micro-organisms that can be found in almost all aquatic and terrestrial environments and strongly affect ecological systems at different spatial scales. The activities of bacteria are profound on the physicochemical features of natural environments, while natural environments shape bacterial behaviours through physical and ...
Li, Hanbing, Zhang, Dayi, Martin, Frank
openaire   +2 more sources

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