Results 81 to 90 of about 1,261,918 (306)

ENVIRONMENTAL SYSTEMS MODELLING AND DIAGNOSIS USING A MULTIPLE MODEL APPROACH [PDF]

Computational Intelligent Systems for Applied Research, 2002
The paper aims to describe the problem of modelling non-linear dynamic systems using a multiple model representation, also known in fuzzy set literature as Takagi-Sugeno model. The basic principle of this approach is to represent the system as an interpolation of locally valid models.
Gasso, Komi, Mourot, Gilles, Ragot, José   +2 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Our research progress in heteroaggregation and homoaggregation of organic π‐conjugated systems

Aggregate, 2021
Construction of crystalline homo/heteroaggregation at micro/nanometer level from organic π‐conjugated systems is of great importance because the controllable morphologies (i.e., size, shape, and dimension) could provide diverse optoelectronic properties ...
Xin Deng, Xiaohui Yu, Jinchong Xiao, Qichun Zhang   +3 more
doaj   +1 more source

Advances and challenges in barcoding pathogenic and environmental Leptospira [PDF]

, 2017
Leptospirosis is a zoonotic bacterial disease of global importance. A large spectrum of asymptomatic animal hosts can carry the infection and contribute to the burden of human disease.
Allan, Kathryn J., Gourant, Cyrille, Guernier, Vanina   +2 more
core   +4 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Melanogenesis and MITF expression in primary melanomas: an immunohistochemical study

Surgical and Experimental Pathology
Background The Microphthalmia-associated transcription factor - MITF is a key regulator of melanogenesis, controlling melanin production and pigment phenotype in melanocytes. It also influences cell differentiation, proliferation, and survival.
Karina Munhoz de Paula Alves Coelho, Jaqueline Stall, Rodrigo Blasius, Bruna Louise Silva, Hercílio Fronza Junior, Paulo Henrique Condeixa de França   +5 more
doaj   +1 more source

New Advances in Bioelectrochemical Systems in the Degradation of Polycyclic Aromatic Hydrocarbons: Source, Degradation Pathway, and Microbial Community

Energies
Because of their high persistence, polycyclic aromatic hydrocarbons (PAHs) are found in a wide range of settings and pose a health risk to both humans and other organisms. Degradation of PAHs is an essential part of environmental management. By combining
Yimeng Feng, Xuya Zhu, Xiulin Huang, Fengxiang Li   +3 more
doaj   +1 more source

Potencial Geoparque de Uberaba (MG): geodiversidade e geoconservação / Geopark potential of Uberaba (MG): geodiversity and geoconservation [PDF]

Sociedade & Natureza, 2013
Uberaba municipality, Western Minas Gerais State, has a great geotouristic potential, regarding itsgeological heritage. The igneous rocks from Serra Geral Formation are found in 12 points, highlightingPonte Alta (40 meters) and Peirópolis III (7 meters ...
Fabiano Tomazini da Conceição, Reinaldo José Bertini, Diego de Souza Sardinha, Letícia Hirata Godoy, Carolina Del Roveri, César Augusto Moreira   +5 more
doaj