Results 121 to 130 of about 1,506,434 (336)

Environmental DNA filtration techniques affect recovered biodiversity

Scientific Reports, 2018
AbstractFreshwater metazoan biodiversity assessment using environmental DNA (eDNA) captured on filters offers new opportunities for water quality management. Filtering of water in the field is a logistical advantage compared to transport of water to the nearest lab, and thus, appropriate filter preservation becomes crucial for maximum DNA recovery ...
Markus Majaneva, Ola H. Diserud, Shannon H. C. Eagle, Erik Boström, Mehrdad Hajibabaei, Torbjørn Ekrem   +5 more
openaire   +3 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

How Does Environmental Inter-annual Variability Shape Aquatic Microbial Communities? A 40-Year Annual Record of Sedimentary DNA From a Boreal Lake (Nylandssjön, Sweden) [PDF]

, 2019
Éric Capo, Johan Rydberg, Julie Tolu, Isabelle Domaizon, Didier Debroas, Richard Bindler, Christian Bigler   +6 more
openalex   +1 more source

Whole-Blood DNA Methylation Analysis Reveals Respiratory Environmental Traits Involved in COVID-19 Severity Following SARS-CoV-2 Infection [PDF]

, 2021
Guillermo Barturen, Elena Carnero‐Montoro, Manuel Martínez‐Bueno, Silvia Rojo‐Rello, Beatriz Sobrino, Clara Alcántara-Domínguez, David Bernardo, Marta E. Alarcón‐Riquelme   +7 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Targeting Terrestrial Vertebrates With eDNA: Trends, Perspectives, and Considerations for Sampling

Environmental DNA
Terrestrial vertebrates are experiencing worldwide population declines and species extinctions. To effectively conserve remaining populations and species, rapid, cost‐effective, and scalable methods are needed to complement longstanding monitoring ...
Joshua P. Newton, Morten E. Allentoft, Philip W. Bateman, Mieke van derHeyde, Paul Nevill   +4 more
doaj   +1 more source

Persistence of Environmental DNA in Freshwater Ecosystems

PLoS ONE, 2011
The precise knowledge of species distribution is a key step in conservation biology. However, species detection can be extremely difficult in many environments, specific life stages and in populations at very low density. The aim of this study was to improve the knowledge on DNA persistence in water in order to confirm the presence of the focus species
Dejean, Tony, Valentini, Alice, Duparc, Antoine, Pellier-Cuit, Stéphanie, Pompanon, Francois, Taberlet, Pierre, Miaud, Claude   +6 more
openaire   +6 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Comparative Study of Fish Diversity in Wanquan River Based on Environmental Technology and Traditional Fishing Gear Survey Methods

Progress in Fishery Sciences
Fish play an important role in maintaining aquatic ecosystems and directly affect the health and stability of aquatic ecosystems. The rapid economic development of the Wanquan River basin has seriously affected the ecological function of fish in the ...
Jun LEI, Yuanyuan SU, Lianzheng YIN, Ruohan ZENG, Ping LI, Yongqiang QIN, Xingwei CAI, Xiaoping DIAO   +7 more
doaj   +1 more source