Results 101 to 110 of about 799,848 (265)

Prediction of Waste Generation Using Machine Learning: A Regional Study in Korea

Urban Science
Accurate forecasting of household waste generation is essential for sustainable urban planning and the development of data-driven environmental policies. Conventional statistical models, while simple and interpretable, often fail to capture the nonlinear
Jae-Sang Lee, Dong-Chul Shin
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Mangrove‐Associated Fish Biodiversity in Selected Philippine Bioregions During the Northeast (Amihan) Monsoon: Insights from eDNA Metabarcoding for Biomonitoring

Environmental DNA
Mangroves play a vital role in supporting diverse associated fauna, yet information on the fish communities they host in the Philippines remains limited.
Christian Jay R. Nob, Yukinobu Isowa, Jessah P. Trillo, Bernadeth Grace S. Pananganan, Earl Kevin T. Cooper, Allyn Duvin P. Hinoguin, Abner C. Evasco Jr., Jerpe E. Honghong Jr., Nonillon M. Aspe, Roger G. Dolorosa, Thesa R. Mendoza, Dixon T. Gevaña, Renan U. Bobiles, Joel Hassan G. Tolentino, Erwin Jones A. Tucong, Phresnofi D. Noval‐Don, Ruby C. Gonzales, Venus E. Leopardas, Tadashi Kajita   +18 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Swab vs rollers: a comparison of methods to collect eDNA from vegetative surfaces

BMC Research Notes
Objective Environmental DNA can be collected from vegetative surfaces circumventing the need for extensive equipment and multiple visits as often required by other sampling methods.
Marina Elisa de Oliveira, Paul Nevill, Mieke van der Heyde   +2 more
doaj   +1 more source

First report of the complete mitochondrial genome of Glyptotendipes pallens (Meigen, 1804) (Diptera: Chironomidae) from Hebei Province, China

Mitochondrial DNA. Part B. Resources
Glyptotendipes pallens (Meigen, 1804) serves as a significant bioindicator for monitoring freshwater ecosystems. Despite the performance of COI barcode analyses on G. pallens, the mitogenome of this taxon remains unassembled and unanalyzed. In this study,
Bingjiao Sun, Mengyu Lv, Tong Wu, Shuyi Li, Xiaolong Lin   +4 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source