Results 81 to 90 of about 1,505,378 (311)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Insight into Invertebrate Community in Solonchak Soil Type Using EDNA Metabarcoding – A Pilot Study

Contemporary Agriculture
Solonchaks are soils characterized by high concentrations of soluble salts. These soils form unique ecosystems that provide habitats for organisms adapted to such extreme conditions.
Lazić Cvijeta, Stefanović Milomir, Tubić Nataša Kočiš, Kuzmanović Ana, Radnović Dragan, Tamindžija Dragana, Milić Stanko, Vasin Jovica, Ninkov Jordana, Djan Mihajla   +9 more
doaj   +1 more source

DNA methylation and socioeconomic status in a Mexican-American birth cohort. [PDF]

, 2018
Background: Maternal social environmental stressors during pregnancy are associated with adverse birth and child developmental outcomes, and epigenetics has been proposed as a possible mechanism for such relationships.
Coker, Eric, Eskenazi, Brenda, Gunier, Robert, HOLLAND, Nina, Huen, Karen   +4 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Epigenetic Effects of Polybrominated Diphenyl Ethers on Human Health. [PDF]

, 2019
Disruption of epigenetic regulation by environmental toxins is an emerging area of focus for understanding the latter's impact on human health. Polybrominated diphenyl ethers (PBDEs), one such group of toxins, are an environmentally pervasive class of ...
Poston, Robert G, Saha, Ramendra N
core   +1 more source

Phylogenetic classification of short environmental DNA fragments [PDF]

Nucleic Acids Research, 2008
Metagenomics is providing striking insights into the ecology of microbial communities. The recently developed massively parallel 454 pyrosequencing technique gives the opportunity to rapidly obtain metagenomic sequences at a low cost and without cloning bias.
Krause, Lutz, Diaz, Naryttza N., Goesmann, Alexander, Kelley, Scott, Nattkemper, Tim Wilhelm, Rohwer, Forest, Edwards, Robert A., Stoye, Jens   +7 more
openaire   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Rediscovering the lost: eDNA detection of freshwater decapods on Réunion Island

Knowledge and Management of Aquatic Ecosystems
Freshwater ecosystems on tropical oceanic islands host unique biodiversity. On Réunion Island, freshwater decapod crustaceans are key indicators of ecosystem health, yet their distribution and conservation status remain poorly documented.
Jannel Lou-Anne, de Mazancourt Valentin, Keith Philippe, Jourand Philippe, Valade Pierre   +4 more
doaj   +1 more source

The European Catfish (Silurus glanis) as an Invasive Species – eDNA Detection Methods

Scientific Papers Animal Science and Biotechnologies, 2023
The European or Wels catfish (Silurus glanis) is an opportunistic apex predator which is the largest freshwater fish species in Europe, making it a popular choice as an angler fish or biological control agent.
Bettina Hegedűs, Zoltán Bagi, Bianka Tóth, Szilvia Kusza   +3 more
doaj