Results 61 to 70 of about 1,505,378 (311)

Genome-specific association study (GSAS) for exploration of variability in hemp (Cannabis sativa)

open access: yesScientific Reports
Hemp (Cannabis sativa L.) is a versatile crop with substantial potential for creating productive, sustainable, and resilient agricultural systems.
Nina Trubanová   +6 more
doaj   +1 more source

Comparative Mitogenomic Analyses of Tanypodinae (Diptera: Chironomidae)

open access: yesInsects
Tanypodinae, a highly diverse subfamily within Chironomidae (Diptera), has been poorly represented in mitochondrial genome (mitogenome) databases, with only a limited number of complete or partial sequences available.
Xiu-Ru Xiao   +7 more
doaj   +1 more source

Sugar additives for MALDI matrices improve signal allowing the smallest nucleotide change (A:T) in a DNA sequence to be resolved [PDF]

open access: yes, 2001
Sample preparation for matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) of DNA is critical for obtaining high quality mass spectra.
Chiu, Norman H. L.   +4 more
core   +1 more source

Environmental versus extra‐organismal DNA [PDF]

open access: yesMolecular Ecology, 2021
Pawlowski, Jan   +2 more
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin [PDF]

open access: yes, 2009
Background: Proteolysis of huntingtin (Htt) plays a key role in the pathogenesis of Huntington's disease (HD). However, the environmental cues and signaling pathways that regulate Htt proteolysis are poorly understood. One stimulus may be the DNA damage
Brundin, Patrick   +4 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanism of DNA Recognition at a Viral Replication Origin [PDF]

open access: yes, 2006
Recognition of the DNA origin by the Epstein-Barr nuclear antigen 1 (EBNA1) protein is the primary event in latentphase genome replication of the Epstein-Barr virus, a model for replication initiation in eukaryotes.
de Prat Gay, Gonzalo   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Composting rapidly degrades DNA from genetically modified plants [PDF]

open access: yes, 2004
Organic farmers are concerned about the use of genetically modified plants (GM plants) in conventional agriculture. The concern is mainly focused on the risk of spreading of pollen or seeds from GM plans to adjacent fields.
Magid, J., Møller, J., Rasmussen, L.D.
core  

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