Results 121 to 130 of about 6,899,226 (260)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Targeting Terrestrial Vertebrates With eDNA: Trends, Perspectives, and Considerations for Sampling

Environmental DNA
Terrestrial vertebrates are experiencing worldwide population declines and species extinctions. To effectively conserve remaining populations and species, rapid, cost‐effective, and scalable methods are needed to complement longstanding monitoring ...
Joshua P. Newton, Morten E. Allentoft, Philip W. Bateman, Mieke van derHeyde, Paul Nevill   +4 more
doaj   +1 more source

Prediction of Waste Generation Using Machine Learning: A Regional Study in Korea

Urban Science
Accurate forecasting of household waste generation is essential for sustainable urban planning and the development of data-driven environmental policies. Conventional statistical models, while simple and interpretable, often fail to capture the nonlinear
Jae-Sang Lee, Dong-Chul Shin
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A Genome-Wide Analysis Reveals Significant Overlap of Transcription and DNA Repair in Stationary Phase Yeast [PDF]

, 2008
The association between transcription and DNA repair is acknowledged as a player in the generation of mutations in a non-random fashion in prokaryotes and eukaryotes.
Leonid Brodsky, Yefim Ronin, Abraham Korol, Eviatar Nevo, Aviv de Morgan, Yechezkel Kashi   +5 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The First International eDNA Workshop in Hong Kong: A beginner's guide for the next‐generation eDNA researcher [PDF]

The field of environmental DNA (eDNA) has rapidly advanced in recent years, providing a non-invasive and time-saving method for assessing biodiversity. The First International Environmental DNA (eDNA) Workshop in Hong Kong was held from 16 to 27 October ...
Hellström, Micaela, Seymour, Mathew, Wang, Zhi, Leray, Matthieu, Moffitt, Jessica, Zeng, Xiaoyi, How, Chun Ming, Guibert, Isis, Jeunen, Gert‐Jan, Ip, Jack Chi Ho, Zhao, Meihong, Elbrect, Vasco, Qian, Cheng, Qin, Xian, Tse, Cham Man, Cutracci, Maxine, Lau, Anthony, Liu, Zifang, Wang, Yifu   +18 more
core   +1 more source

Mangrove‐Associated Fish Biodiversity in Selected Philippine Bioregions During the Northeast (Amihan) Monsoon: Insights from eDNA Metabarcoding for Biomonitoring

Environmental DNA
Mangroves play a vital role in supporting diverse associated fauna, yet information on the fish communities they host in the Philippines remains limited.
Christian Jay R. Nob, Yukinobu Isowa, Jessah P. Trillo, Bernadeth Grace S. Pananganan, Earl Kevin T. Cooper, Allyn Duvin P. Hinoguin, Abner C. Evasco Jr., Jerpe E. Honghong Jr., Nonillon M. Aspe, Roger G. Dolorosa, Thesa R. Mendoza, Dixon T. Gevaña, Renan U. Bobiles, Joel Hassan G. Tolentino, Erwin Jones A. Tucong, Phresnofi D. Noval‐Don, Ruby C. Gonzales, Venus E. Leopardas, Tadashi Kajita   +18 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source