Results 21 to 30 of about 1,505,378 (311)

Detection of Epigenomic Network Community Oncomarkers [PDF]

open access: yes, 2016
In this paper we propose network methodology to infer prognostic cancer biomarkers based on the epigenetic pattern DNA methylation. Epigenetic processes such as DNA methylation reflect environmental risk factors, and are increasingly recognised for their
Bartlett, Thomas E., Zaikin, Alexey
core   +2 more sources

Sponges as natural environmental DNA samplers [PDF]

open access: yesCurrent Biology, 2019
At a time of unprecedented impacts on marine biodiversity, scientists are rapidly becoming persuaded by the potential of screening large swathes of the oceans through the retrieval, amplification and sequencing of trace DNA fragments left behind by marine organisms; an approach known as 'environmental DNA' (eDNA) [1].
Mariani, Stefano   +3 more
openaire   +4 more sources

Repair, abort, ignore? Strategies for dealing with UV damage [PDF]

open access: yes, 2011
DNA repair is a prominent member of the nuclear transactions triad (replication, transcription, and repair). Sophisticated mechanisms govern the cellular process of decision-making (to repair or not to repair, to proceed with cell cycle or not and ...
Khalil, Hilal S.   +2 more
core   +3 more sources

Metagenomics: DNA sequencing of environmental samples [PDF]

open access: yesNature Reviews Genetics, 2005
Although genomics has classically focused on pure, easy-to-obtain samples, such as microbes that grow readily in culture or large animals and plants, these organisms represent only a fraction of the living or once-living organisms of interest. Many species are difficult to study in isolation because they fail to grow in laboratory culture, depend on ...
Tringe, Susannah Green, Rubin, Edward M.
openaire   +3 more sources

Water, water everywhere: environmental DNA can unlock population structure in elusive marine species [PDF]

open access: yesRoyal Society Open Science, 2018
Determining management units for natural populations is critical for effective conservation and management. However, collecting the requisite tissue samples for population genetic analyses remains the primary limiting factor for a number of marine ...
Kim M. Parsons   +3 more
doaj   +1 more source

Making environmental DNA count [PDF]

open access: yesMolecular Ecology Resources, 2015
The arc of reception for a new technology or method – like the reception of new information itself – can pass through predictable stages, with audiences’ responses evolving from ‘I don't believe it’, through ‘well, maybe’ to ‘yes, everyone knows that’ to, finally, ‘old news’.
openaire   +2 more sources

Environmental variables, habitat discontinuity and life history shaping the genetic structure of Pomatoschistus marmoratus [PDF]

open access: yes, 2014
Coastal lagoons are semi-isolated ecosystems exposed to wide fluctuations of environmental conditions and showing habitat fragmentation. These features may play an important role in separating species into different populations, even at small spatial
A Pérez-Ruzafa   +119 more
core   +3 more sources

The California environmental DNA “CALeDNA” program [PDF]

open access: yes, 2019
AbstractGlobal change is leading to habitat shifts that threaten species persistence throughout California’s unique ecosystems. Baseline biodiversity data provide opportunities for ecosystems to be managed for community complexity and connectivity.
Meyer, Rachel   +24 more
openaire   +1 more source

Estimating species richness using environmental DNA [PDF]

open access: yesEcology and Evolution, 2016
AbstractThe foundation for any ecological study and for the effective management of biodiversity in natural systems requires knowing what species are present in an ecosystem. We assessed fish communities in a stream using two methods, depletion‐based electrofishing and environmental DNA metabarcoding (eDNA) from water samples, to test the hypothesis ...
Olds, Brett P.   +12 more
openaire   +4 more sources

MiFish, a set of universal PCR primers for metabarcoding environmental DNA from fishes: detection of more than 230 subtropical marine species [PDF]

open access: yesRoyal Society Open Science, 2015
We developed a set of universal PCR primers (MiFish-U/E) for metabarcoding environmental DNA (eDNA) from fishes. Primers were designed using aligned whole mitochondrial genome (mitogenome) sequences from 880 species, supplemented by partial mitogenome ...
M. Miya   +11 more
doaj   +1 more source

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