Results 91 to 100 of about 22,349,223 (341)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Understanding student learning in environmental education in Aotearoa New Zealand

, 2011
This paper seeks to provide a perspective on environmental education in Aotearoa New Zealand. To contextualise this perspective, it illustrates how environmental, socio-cultural and political imperatives have shaped the development of environmental ...
Eames, Chris W., Barker, Miles
core   +1 more source

Indigenous-led toxic tours opening pathways for (re)connecting to place, people and all creation

Australian Journal of Environmental Education, 2023
Home to nine Tribal Nations, the northeastern corner of Oklahoma (US) is a place of immense resilience, cultural beauty and attachment to place. Horrifically, however, this same area is also home to massive environmental assaults that have occurred as a ...
Bobbie Chew Bigby, Rebecca Jim, Earl Hatley   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Daily Planet: The Newsletter of the Alliance for New Jersey Environmental Education, Fall 2008

, 2008
This is the newsletter for Alliance for New Jersey Environmental Education (ANJEE), which is a privately supported, non-profit organization whose members are committed to using environmental education as an instrument for change in New Jersey. This issue

core   +1 more source

The Effect of a Nature-Based Environmental Education Program on Children’s Environmental Attitudes and Behaviors: A Randomized Experiment with Primary Schools

Sustainability, 2020
The evidence about the effects of nature-based instruction on pro-environmentalism is uncompelling, mainly due to a lack of controlled experiments. This hinders causal claims and the provision of intervention guidelines.
Silvia Collado, Claudio D. Rosa, J. Corraliza   +2 more
semanticscholar   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The Daily Planet: The Newsletter of the Alliance for New Jersey Environmental Education, Summer 2008

, 2008
This is the newsletter for Alliance for New Jersey Environmental Education (ANJEE), which is a privately supported, non-profit organization whose members are committed to using environmental education as an instrument for change in New Jersey. This issue

core   +1 more source

Integration of environmental education in elementary schools

Journal of Physics, Conference Series, 2020
This study aims to determine the opinions and knowledge of teachers regarding the integration of environmental education in the learning process in the classroom for elementary school students. This research uses survey method.
E. Sukma, S. Ramadhan, Vivi Indriyani
semanticscholar   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source