Results 101 to 110 of about 12,174,591 (329)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Environmental education for nurturing nature: Assessment of environmental education in nature protection in Nigeria

Social Sciences and Humanities Open
Achieving sustainable development in Nigeria is inextricably linked to preserving the country's natural environment, species and biodiversity. However, human activities continue to degrade the natural environment, resulting in the loss of vital resources.
Anthony Kola-Olusanya, Peter S. Adewale, Florence Yusuf, Ola T. Odekeye   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Forest Schools and environmental attitudes: A case study of children aged 8–11 years

Cogent Education, 2015
There is growing evidence that children in the UK are suffering from a lack of engagement with nature and the outdoor environment. This paper investigates the attitudes of children towards the natural environment and focuses on Forest School programmes ...
Christina Turtle, Ian Convery, Katie Convery   +2 more
doaj   +1 more source

Environmental education in transition: A critical review of recent research on climate change and energy education

The Journal of Environmental Education, 2019
The transition from centralized energy systems based on fossil fuels to renewable-based systems is a macro-level societal shift necessitated by climate change.
Simon N. Jorgenson, J. Stephens, Beth White   +2 more
semanticscholar   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Participação em políticas públicas para conservação de matas ciliares no Estado de São Paulo

Ambiente & Sociedade, 2012
O presente artigo visa a contribuir para os diálogos sobre políticas públicas relacionadas à conservação e restauração de matas ciliares no estado de São Paulo, considerando as possibilidades de participação social em sua formulação e implementação.
Maria Castellano, Marcos Sorrentino
doaj   +1 more source

The relationships between technology and open education in the development of a resilient higher education [PDF]

, 2010
The place of technology in the development of coherent educational responses to environmental and socio-economic disruption is here placed under scrutiny. One emerging area of interest is the role of technology in addressing more complex learning futures,
Hall, Richard, Winn, Joss
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Cross-bridging green chemistry education and environmental chemistry education

Sustainable Chemistry for the Environment
Green chemistry education has been the object of intensive attention, research and explorations in the last decades; environmental chemistry education has received alternating attention. Both green chemistry and environmental chemistry are concerned with
Liliana Mammino
doaj   +1 more source