Results 81 to 90 of about 5,408,281 (241)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Typical battlefield infrared background detection method based on multi band fusion

Discover Applied Sciences
Intelligent battlefield environment recognition is crucial for active camouflage technology. Enhancing detection capabilities for various environments is essential for target survival.
Bentian Hao, Weidong Xu, Xin Yang
doaj   +1 more source

FDTool: a Python application to mine for functional dependencies and candidate keys in tabular data [version 1; peer review: 2 approved]

F1000Research, 2018
Functional dependencies (FDs) and candidate keys are essential for table decomposition, database normalization, and data cleansing. In this paper, we present FDTool, a command line Python application to discover minimal FDs in tabular datasets and infer ...
Matt Buranosky, Elmar Stellnberger, Emily Pfaff, David Diaz-Sanchez, Cavin Ward-Caviness   +4 more
doaj   +1 more source

Organic Farming - An efficient and integrated system approach responding to pressing challenges [PDF]

, 2010
- One strict and easily understandable rule in organic farming such as the ban of synthetic fertilisers often results in a number of environmental benefits.
Niggli, Urs, Schader, Christian, Stolze, Matthias   +2 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

High Time for Conservation: Adding the Environment to the Debate on Marijuana Liberalization [PDF]

, 2015
The liberalization of marijuana policies, including the legalization of medical and recreational marijuana, is sweeping the United States and other countries.
Anne G. Short Gianotti, David N. Dralle, Jeanette K. Howard, Jennifer K. Carah, Mourad W. Gabriel, Sally E. Thompson, Scott D. Bauer, Stephanie M. Carlson   +7 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Space environmental effects on materials [PDF]

The design of long life platforms and structures for space is discussed in terms of the space environmental effects on the materials used. Vacuum, ultraviolet radiation, and charged particle radiation are among the factors considered.
Schwinghmaer, R. J.
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

A probe for NIR-II imaging and multimodal analysis of early Alzheimer’s disease by targeting CTGF

Nature Communications
To date, earlier diagnosis of Alzheimer’s disease (AD) is still challenging. Recent studies revealed the elevated expression of connective tissue growth factor (CTGF) in AD brain is an upstream regulator of amyloid-beta (Aβ) plaque, thus CTGF could be an
Cao Lu, Cong Meng, Yuying Li, Jinling Yuan, Xiaojun Ren, Liang Gao, Dongdong Su, Kai Cao, Mengchao Cui, Qing Yuan, Xueyun Gao   +10 more
doaj   +1 more source