Results 151 to 160 of about 2,730,918 (321)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Teaching Systems Thinking and System Dynamics in Engineering, Ecology and Environmental Sciences: A Concise Course Based on the Water Management and Population Dynamics Models

, 2023
Vladimir Krivtsov, Irene Pluchinotta, Alessandro Pagano   +2 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

THE ROLE OF GEOLOGY IN ENVIRONMENTAL ENGINEERING

Journal of Chemists, Technologists and Environmentalists
Environmental engineering is an interdisciplinary science that relies on the knowledge of a number of other "basic" sciences - chemistry, mathematics, physics, biology and geology.
Dragana Dogančić, Anita Ptiček Siročić   +1 more
doaj   +1 more source

Terpenoid indole alkaloid biosynthesis in Catharanthus roseus: effects and prospects of environmental factors in metabolic engineering [PDF]

, 2021
Yongliang Liu, Barunava Patra, Sanjay K. Singh, Priyanka Paul, Yan Zhou, Yongqing Li, Ying Wang, Sitakanta Pattanaik, Ling Yuan   +8 more
openalex   +1 more source

Engineering model test plan. Space storable propellant module environmental control technology [PDF]

Test program for engineering model of thermal control system of space storable propellant module in simulated ...
Haroldsen, O. O., Porter, R. N.
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Integrating Community Engagement and Service Learning into Environmental Engineering Curricula

Education Sciences
Engineering education is evolving to train students to work more closely with communities to support holistic sustainability. This has increasingly involved collaborative and participatory research models that address environmental justice challenges ...
Michelle Henderson, Abby Vidmar, Maya Trotz, Deirdre Cobb-Roberts, E. Christian Wells   +4 more
doaj   +1 more source

The Third International Conference on Energy Engineering and Environmental Protection

, 2019

openalex   +1 more source

Effect of Boundary Conditions in Segmental Lining Model on its Sectional Force [PDF]

, 2016
Chaiyaput, S., Graduate student, Department of Civil and Environmental Engineering, Nagaoka University of Technology, Professor, Department of Civil and Environmental Engineering, Nagaoka University of Technology, Sugimoto, M.   +3 more
core   +1 more source