Results 51 to 60 of about 605,346 (361)

Environmental Enrichment for Rats and Mice Housed in Laboratories: A Metareview

Animals, 2022
Environmental enrichment has been widely studied in rodents, but there is no consensus on what enrichment should look like or what it should achieve. Inconsistent use of the term “enrichment” creates challenges in drawing conclusions about the quality of
Anna S. Ratuski, Daniel M. Weary
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Effects of Environmental Enrichment on Hippocampal Electrophysiological Changes in the Pentylenetetrazole Model of Epilepsy

Archives of Epilepsy, 2016
Objectives:Epilepsy is a neurological disorder characterized by functional/morphological changes in the hippocampus. These functional changes arise as increase or decrease in synaptic plasticity in experimental animals.
Seval KELOĞLAN, Soner BİTİKTAŞ, Nazan DOLU, Cem SÜER, Seda ARTIŞ   +4 more
doaj   +1 more source

Environmental enrichment and the sensory brain: the role of enrichment in remediating brain injury

Frontiers in Systems Neuroscience, 2014
The brain’s life-long capacity for experience-dependent plasticity allows adaptation to new environments or to changes in the environment, and to changes in internal brain states such as occurs in brain damage.
Dasuni Sathsara Alwis, Ramesh eRajan
doaj   +1 more source

Nanoscale spatially resolved mapping of uranium enrichment in actinide-bearing materials [PDF]

, 2019
Spatially resolved analysis of uranium isotopes in small volumes of actinide-bearing materials is critical for a variety of technical disciplines, including earth and planetary sciences, environmental monitoring, bioremediation, and the nuclear fuel cycle. However, achieving sub-nanometer scale spatial resolution for such isotopic analysis is currently
arxiv   +1 more source

Gene-network inference by message passing [PDF]

Journal of Physics: Conference Series 95 (2008) 012016, 2008
The inference of gene-regulatory processes from gene-expression data belongs to the major challenges of computational systems biology. Here we address the problem from a statistical-physics perspective and develop a message-passing algorithm which is able to infer sparse, directed and combinatorial regulatory mechanisms.
arxiv   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Environmental Enrichment Protects Against Sepsis-Associated Encephalopathy-Induced Learning and Memory Deficits by Enhancing the Synthesis and Release of Vasopressin in the Supraoptic Nucleus

Journal of Inflammation Research, 2022
Shan Jiang,1,* Yong-Qiang Wang,2,* Yifei Tang,1 Xi Lu,1 Dan Guo1 1Department of Rehabilitation Medicine, the China-Japan Friendship Hospital, Beijing, 100029, People’s Republic of China; 2Department of Ophthalmology, the Sunshine Union Hospital ...
Jiang S, Wang YQ, Tang Y, Lu X, Guo D
doaj  

Effects of nutrient enrichment on seagrass population dynamics: evidence and synthesis from the biomass-density relationships [PDF]

, 2013
The available data from experimental and descriptive studies on seagrass biomass and density responses to nutrient enrichment were analysed to assess the intraspecific mechanisms operating within seagrass populations and whether biomass-density ...
Agawin, Apostolaki, Brooker, Brun, Bulthuis, Burkholder, Cabaço, Cabaço, Cabaço, Cabaço, Chu, Chu, Duarte, Duarte, Duarte, Fertig, Fraterrigo, García-Marín, Heck, Hemminga, Hughes, Jackson, Katwijk, Koch, Koch, Kroon, Kuo, Lee, Lee, Lopez y Royo, Manly, Marbà, Marbà, Marbà, Martínez-Crego, Miller, Morris, Morris, Morris, Morris, Morris, Morris, Müller, Peralta, Phillips, Ralph, Ralph, Robinson, Romero, Romero, Schmidt, Schwinning, Scrosati, Short, Short, Short, Sokal, Sousa, Steen, Timmerman, Tomasko, Turner, Turner, Turner, Tussenbroek, Udy, Udy, Udy, Udy, Underwood, Waycott, Weller, Weller, Westoby, White, Yoda   +75 more
core   +1 more source