Results 61 to 70 of about 605,346 (361)
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Deformable Object Tracking with Gated Fusion [PDF]
IEEE Transactions on Image Processing, 2019, 2018 The tracking-by-detection framework receives growing attentions through the integration with the Convolutional Neural Networks (CNNs). Existing tracking-by-detection based methods, however, fail to track objects with severe appearance variations. This is because the traditional convolutional operation is performed on fixed grids, and thus may not be ...
arxiv +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Environmental Enrichment for Broiler Breeders: An Undeveloped Field
Frontiers in Veterinary Science, 2017 Welfare problems, such as hunger, frustration, aggression, and abnormal sexual behavior, are commonly found in broiler breeder production. To prevent or reduce these welfare problems, it has been suggested to provide stimulating enriched environments. We
Anja B. Riber +3 more
doaj +1 more source
Environmental Racism and Biased Methods of Risk Assessment [PDF]
, 1996 Based on analysis of a risk assessment for a proposed Louisiana uranium enrichment facility, the authors argue that environmental injustice occurs when assessors\u27 scientific methods cause de facto ...
Shrader-Frechette, Kristin S. +1 more
core +1 more source
Influence of Enrichment on the Behavior of New Zealand White Rabbits and Cynomolgus Macaques in a Research Setting During Their Quarantine Period [PDF]
, 2022 Enrichment is an excellent tool used to refine animal husbandry practices in laboratory animal medicine. When animals first arrive at a facility, the animals are given a quarantine period to ensure they are healthy, and to allow the animals to acclimate ...
Sheehy, James
core +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Influence of bedding on behavior and reproductive efficiency of pregnant sows
Boletim de Indústria Animal, 2015 Ensuring animal welfare in the production chain has been an ever-present requirement in commercial relationships among producer and export markets. The use of bedding is indicated as a means of facilitating the comfort and welfare of animals, and affords
Maria Luísa Appendino Nunes +2 more
doaj +2 more sources
A spatial judgement task to determine background emotional state in laboratory rats (Rattus norvegicus) [PDF]
, 2008 Humans experiencing different background emotional states display contrasting cognitive (e.g. judgement) biases when responding to ambiguous stimuli. We have proposed that such biases may be used as indicators of animal emotional state.
Abou-Ismail +43 more
core +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source