Results 71 to 80 of about 260,132 (290)

Effect of environmental enrichment on productive performance and welfare aspects in fattening rabbits

open access: yesItalian Journal of Animal Science, 2011
Fattening rabbits are conventionally housed in 2 animals per cages, according to the local tradition. Presently in Europe no EU Directive exists on cage dimensions for these animals, while in some Countries local Codes (i.e.Ministry of Agriculture, U.K.,
M. Verga   +3 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Outside enclosure and additional enrichment for dairy goats – a preliminary study

open access: yesActa Veterinaria Scandinavica, 2012
Background Dairy goats are commonly housed at a space allowance of 0.7 – 0.8 m2/goat in commercial Norwegian goat herds, which is very low compared to regulations and recommendations in other European countries.
Bøe Knut Egil   +2 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Prevalence and Perceived Effects of Enrichment Elements in Outdoor Areas on the Behavior and Welfare of Group-Housed Horses

open access: yesInternational Journal of Equine Science
Environmental enrichment has the potential to cultivate positive equine welfare through agency-driven opportunities for socialization, foraging, and exploration.
Nicole Miggitsch   +2 more
doaj   +1 more source

THE BEHAVIOURAL REACTION OF WEANERS TO HANGING TOYS: WOODEN BALL AND AROMATIZED WOODEN BALL – WAY TO REDUCE AGGRESSION AFTER MIXING [PDF]

open access: yesJournal of Central European Agriculture, 2008
The behaviour of weaners after mixing housed in pens equipped with hanging wooden ball, aromatized with vanilla fluid hanging wooden ball and without enrichment was evaluated.
Jacek NOWICKI   +2 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Home - About - Disclaimer - Privacy