Results 71 to 80 of about 1,450,328 (287)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Environmental Ethics through Value-Based Education

open access: yesBangladesh Journal of Bioethics
Environmental ethics is the subject in philosophy that examines the moral relationship of human beings to the environment and its non-human species. It concerns human’s ethical relationship with the natural environment.
Ravichandran Moorthy   +1 more
doaj   +1 more source

Environmental vices as ethical and anthropological roots of the environmental crisis

open access: yesStudia Ecologiae et Bioethicae, 2020
The root of environmental crisis is not only the failure to recognize the intrinsic value of the non-human world, but it can also be perceived as a failure in moral excellence and in the cultivation of virtue.
Dominika Dzwonkowska
doaj   +1 more source

Epilogue [PDF]

open access: yes, 2009
The Environmental Responsibility Reader is a definitive collection of classic and contemporary environmental works that offers a comprehensive overview of the issues involved in environmental responsibility, steering the reader through each development ...
Blackmore, Chris   +2 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Investigation of Pre-service Teachers' Environmental Ethics Awareness and Attitudes towards Sustainable Environment

open access: yesAnadolu Üniversitesi Eğitim Fakültesi dergisi
The aim of this study was to determine the environmental ethics awareness and sustainable environmental attitudes of pre-service teachers to reveal the teachers’ access to the content specified in undergraduate education.
Birsen Berfu Akaydın, Aslı Eşme
doaj   +1 more source

Ethics of Social Consequences and Evolutionary Ontology in Contemporary Environmental Ethics

open access: yesProfil, 2019
The article deals with an analysis, comparison and evaluation of Evolutionary Ontology by Josef Šmajs and Ethics of Social Consequences by Vasil Gluchman.
Martin Pazdera
doaj   +1 more source

Paul Taylors Biocentric Ethics: A Survey of Contemporary Environmental Conflicts [PDF]

open access: yes, 2019
This work is on Paul Taylors Biocentric Ethics: A Survey of Contemporary Environmental Conflicts. When we accept the concept of biocentrism there is bound to exist conflicts between interests and cultural values of humans and the well-being of nonhuman ...
Big-Alabo, Sotonye
core  

Gaia as science made myth: Implications for environmental ethics [PDF]

open access: yes, 1996
This is a PDF version of an article published in Studies in Christian Ethics© 1996. The definitive version is available at http://sce.sagepub.comThis article discusses the Gaia hypothesis - the earth as a giant ecosystem. It comments on scientific models
Deane-Drummond, Celia
core   +1 more source

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