Results 51 to 60 of about 611,538 (299)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Interdisciplinary Foundations for Environmental and Sustainability Ethics: An Introduction
Ethics in Progress, 2014 This article introduces the special issue for Ethics in Progress entitled Environment, ethics, and sustainability: Crossroads of our future. Despite four decades of intense development in the field of academic and professional environmental ethics ...
Małgorzata Dereniowska, Jason Matzke
doaj +3 more sources
Energy Equality and the Challenges of Population Growth
Relations, 2018 This paper points out the relation between population growth and energy justice in a finite world. Reflecting on the meaning of limits, I propose to look at energy justice in a broader sense: restoring a safe and more equal operating space for humanity ...
Andrea Natan Feltrin
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Environmental ethics and environmental anthropology [PDF]
, 2017 Includes bibliographical references (pages 286-287).Is there a particular angle that environmental anthropology offers environmental ethics? Local peoples find that both their natural and their social systems are jeopardized by global forces, requiring ...
Routledge, Earthscan, publisher +1 more
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Critical notice of Environmental ethics: values in and duties to the natural world [PDF]
, 2020 Critical notice of citations of Rolston's published book Environmental Ethics: Values in and Duties to the Natural ...
Rolston, Holmes, 1932-, author
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VertigO, 2020 This article investigates new convergences between animal ethics and environmental ethics by focusing on the effects as well as the causes of climate change.
Michel Bourban , Lisa Broussois
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Uma Ética Holística para as Gerações Futuras: caminho para o Novo Direito Ambiental
Revista Interdisciplinar de Direito, 2016 This article discusses the relevance to investigate the concerns based on ethics and on environmental law, with a view to defend and preserve the environment for current and future generations as possible, because it is a right that link ...
Mária de Fátima Alves São Pedro
doaj +3 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source