Results 111 to 120 of about 2,506,056 (353)

Assessing the influence of environmental context on responses to noise exposure in the city of Toronto

, 2021
Desislava Stevanova
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Environmental impact of atmospheric NH3 emissions under present and future conditions in the eastern United States

Geophysical Research Letters, 2008
Recent regulations require large‐scale emission reductions of NOx and SO2 in the eastern United States. These emission changes will alter the partitioning of ammonia between the gas and particle phases.
R. W. Pinder, A. B. Gilliland, R. L. Dennis   +2 more
doaj   +1 more source

Environmental to bacco smoke exposure and The impact of a smoking ban in internet cafes, pubs and billiard halls around a university in Korea [PDF]

, 2019
Kwonchul Ha, Donguk Park
openalex   +1 more source

A Hospital Based Study Using Micro-Environmental Modelling Demonstrating the Association between Coronary Artery Calcification Score and Cumulative Air Pollutant Exposure: An Explorative Study

, 2023
Ankit Viramgami, Mehul Madia, Moinuddhin Mansuri, Yashpal Rana, Megha Sheth, Samir Patel, Millin Garachh, Pooja Vyas, Preet Kotak, Niyati Patel, Dinesh Patel, Rakesh Balachandar   +11 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Preparation of montmorillonite/chitosan/γ-polyglutamic acid nanoparticles and evaluation of their adsorption and antibacterial performance

Scientific Reports
In this study, montmorillonite (MMT)/chitosan (CS)/γ-polyglutamic acid (γ-PGA) nanoparticles were synthesized using MMT, CS, and γ-PGA as the matrix materials, with amino silane as the crosslinking agent.
Zuolong Yu, Chen Chen, Jiatao Wang, Yunxiao Wei, Changchun Fu, Dan Lu, Chao Han, Shiying Shen, Yan Shen   +8 more
doaj   +1 more source

A new approach methodology to identify tumorigenic chemicals using short-term exposures and transcript profiling

Frontiers in Toxicology
Current methods for cancer risk assessment are resource-intensive and not feasible for most of the thousands of untested chemicals. In earlier studies, we developed a new approach methodology (NAM) to identify liver tumorigens using gene expression ...
Victoria Ledbetter, Victoria Ledbetter, Scott Auerbach, Logan J. Everett, Beena Vallanat, Anna Lowit, Gregory Akerman, William Gwinn, Leah C. Wehmas, Michael F. Hughes, Michael Devito, J. Christopher Corton   +11 more
doaj   +1 more source

A meta-analysis of selected near-road air pollutants based on concentration decay rates

Heliyon, 2019
Traffic-related air pollution has been associated with various health risks for human populations living near roadways. Understanding the relationship between traffic density and dispersion of vehicle-released air pollutants is important for assessing ...
Shi V. Liu, Fu-lin Chen, Jianping Xue
doaj   +1 more source

RESIDENTIAL HISTORY, DURATION OF ENVIRONMENTAL AND NEIGHBORHOOD SOCIOECONOMIC EXPOSURES AND MENTAL AND CARDIOVASCULAR HEALTH [PDF]

, 2011
Kateryna Fuks, Natalie Riedel, Nico Dragano, Anja Viehmann, Ulla Roggenbuck, Michael R. Nonnemacher, Stefan Möhlenkamp, Susanne Moebus, Raimund Erbel, Karl‐Heinz Jöckel, Barbara Hoffmann   +10 more
openalex   +1 more source