Results 151 to 160 of about 7,641,268 (406)

Reading, Writing, and Breathing [PDF]

, 2005
This report looks at the distribution of air toxics, respiratory hazard, and school children in the state of California. The report finds evidence of disproportionate exposure and a potential link between such exposure and school-level academic ...
James Sadd, Manuel Pastor, Rachel Morello-Frosch   +2 more
core  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Environmental noise exposure. [PDF]

Environmental Health Perspectives, 1998
Willy Passchier-Vermeer, Wim F. Passchier   +1 more
openaire   +2 more sources

Simple traffic measures significantly reduce the exposure of primary school children to NO₂ [PDF]

, 2019
According to Public Health England (PHE, 2019) air quality is the largest environmental health risk in the UK; long-term exposure to air pollution claims some 28-36,000 premature deaths each year.
Cameron, Valerie, Cook, Tobin, Oduyemi, Kehinde, Rirsche, Cathy   +3 more
core  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

A new approach methodology to identify tumorigenic chemicals using short-term exposures and transcript profiling

Frontiers in Toxicology
Current methods for cancer risk assessment are resource-intensive and not feasible for most of the thousands of untested chemicals. In earlier studies, we developed a new approach methodology (NAM) to identify liver tumorigens using gene expression ...
Victoria Ledbetter, Victoria Ledbetter, Scott Auerbach, Logan J. Everett, Beena Vallanat, Anna Lowit, Gregory Akerman, William Gwinn, Leah C. Wehmas, Michael F. Hughes, Michael Devito, J. Christopher Corton   +11 more
doaj   +1 more source

Changes in Landscape Greenness and Climatic Factors over 25 Years (1989–2013) in the USA

Remote Sensing, 2017
Monitoring and quantifying changes in vegetation cover over large areas using remote sensing can be achieved using the Normalized Difference Vegetation Index (NDVI), an indicator of greenness. However, distinguishing gradual shifts in NDVI (e.g., climate
Maliha S. Nash, James Wickham, Jay Christensen, Timothy Wade   +3 more
doaj   +1 more source

Is Environmental Justice Good for White Folks? [PDF]

This paper examines spatial variations in exposure to toxic air pollution from industrial facilities in urban areas of the United States, using geographic microdata from the U.S.
Grace Chang, Helen Scharber, James Boyce, Michael Ash   +3 more
core  

A Meta-Analysis of the Willingness to Pay for Reductions in Pesticide Risk Exposure [PDF]

The use of environmental policy instruments such as eco-labelling and pesticide taxes should preferably be based on disaggregate estimates of the individuals' willingness to pay (WTP) for pesticide risk reductions.
Florax, Raymond J.G.M., Nijkamp, Peter, Travisi, Chiara M.   +2 more
core   +4 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source