Epigenetics and environmental exposures [PDF]
Journal of Epidemiology and Community Health, 2011 It is becoming increasingly apparent that genetic factors are inadequate to fully explain many processes that shape development and disease. For example, monozygotic twin pairs, despite sharing identical DNA sequences, are often discordant for many traits and diseases, indicating that the same genotype can give rise to distinct phenotypes.
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Predicting molecular initiating events using chemical target annotations and gene expression
BioData Mining, 2022 Background The advent of high-throughput transcriptomic screening technologies has resulted in a wealth of publicly available gene expression data associated with chemical treatments.
Joseph L. Bundy +5 more
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Environmental Exposures and Hepatocellular Carcinoma [PDF]
Journal of Clinical and Translational Hepatology, 2016 Infection with hepatitis B and/or hepatitis C virus is a well-established risk factor for the development of hepatocellular carcinoma (HCC). However, it is now clear that certain occupational, environmental, and lifestyle factors also play a role in cancer development.
Hui-Chen Wu, Regina M. Santella
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Mapping environmental injustices: pitfalls and potential of geographic information systems in assessing environmental health and equity. [PDF]
, 2002 Geographic Information Systems (GIS) have been used increasingly to map instances of environmental injustice, the disproportionate exposure of certain populations to environmental hazards.
Austin R +16 more
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A framework for expanding aqueous chemistry in the Community Multiscale Air Quality (CMAQ) model version 5.1 [PDF]
Geoscientific Model Development, 2017 This paper describes the development and implementation of an extendable aqueous-phase chemistry option (AQCHEM − KMT(I)) for the Community Multiscale Air Quality (CMAQ) modeling system, version 5.1.
K. M. Fahey +9 more
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Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population [PDF]
, 2012 Background: The ‘exposome’ represents the accumulation of all environmental exposures across a lifetime. Topdown strategies are required to assess something this comprehensive, and could transform our understanding of how environmental factors affect ...
Athersuch, Toby J. +10 more
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Environmental Exposures during Puberty: Window of Breast Cancer Risk and Epigenetic Damage. [PDF]
, 2020 During puberty, a woman's breasts are vulnerable to environmental damage ("window of vulnerability"). Early exposure to environmental carcinogens, endocrine disruptors, and unhealthy foods (refined sugar, processed fats, food additives) are hypothesized ...
Aljaber, Dana +19 more
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Influence of Environmental Risk on the Financial Structure of Oil and Gas Projects [PDF]
, 2013 The risk profile of a Build-Operate-Transfer (BOT) project affects its debt service ability. In particular, the total risk profile of an oil and gas project is heavily influenced by its environmental risk exposure. However, this risk is often not given a
De Marco, Alberto, Karsybayeva, B.
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Technical challenges and solutions in representing lakes when using WRF in downscaling applications [PDF]
Geoscientific Model Development, 2015 The Weather Research and Forecasting (WRF) model is commonly used to make high-resolution future projections of regional climate by downscaling global climate model (GCM) outputs.
M. S. Mallard +7 more
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Wrangling environmental exposure data: guidance for getting the best information from your laboratory measurements. [PDF]
, 2019 BACKGROUND:Environmental health and exposure researchers can improve the quality and interpretation of their chemical measurement data, avoid spurious results, and improve analytical protocols for new chemicals by closely examining lab and field quality ...
Dodson, Robin E +3 more
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