Results 181 to 190 of about 13,240,040 (288)

Genetic and environmental factors underlying the associations between attachment styles and mental and physical health. [PDF]

J Pers Soc Psychol
Dugan KA, Kunkel JJ, Vacaru SV, Fraley RC, Waters TEA, McGue M, Krueger RF, Roisman GI.   +7 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Effects of family genetic risk scores and environmental factors on risk of schizophrenia and bipolar disorder. [PDF]

Mol Psychiatry
Robinson N, Ploner A, Ohlsson H, Lichtenstein P, Kendler KS, Bergen SE.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Association of Demographic, Clinical, and Environmental Factors With Disease Severity in Adult Myasthenia Gravis: A Multicenter Cross-Sectional Study. [PDF]

CNS Neurosci Ther
Liu H, Wang J, Zhu W, Chang T, Chen H, Sun C, Guo R, Ruan Z, Bi F, Li J, Wang J, Zhang S, Wen Q, Wang Y, Li Y, Xie N, Jiang Y, Lu Y, Di L, Xu M, Wang M, Chen H, Wen X, Duo J, Huang Y, Feng H, Zhou H, Da Y.   +27 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Editorial: Lifestyle and environmental factors and human fertility. [PDF]

Front Endocrinol (Lausanne)
Ribeiro ML.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Coccidioidomycosis Exposure Assessed by Skin Testing and Environmental Factors in Baja California, Mexico. [PDF]

J Fungi (Basel)
Candolfi-Arballo O, Dávila-Lezama A, Narváez-Hernández E, Ontiveros-Duries M, Soto-Reyes JM, Galeana-Pizaña JM, Castillo-Martínez NA, Castañón-Olivares LR.   +7 more
europepmc   +1 more source