Results 41 to 50 of about 166,986 (256)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Landscape and Marine Environmental Factors Jointly Regulate the Intertidal Species Richness and Community Structure in the Islands of South Korea

Diversity, 2023
Most studies on island biogeography have focused on the terrestrial taxa; however, there are few studies on the drivers of diversity and community structure of intertidal organisms on islands. We evaluated the effect of landscape and marine environmental
Min-Ki Lee, Yong-Ju Lee, Chang-Bae Lee
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Temporal Stack Speckle and Target Filtering for Environmental Applications

IGARSS 2022 - 2022 IEEE International Geoscience and Remote Sensing Symposium, 2022
SAR images are affected by speckle noise and the presence of ephemeral targets. We propose a method to filter both from individual images in a temporal stack through the use of a modified Frozen Background Reference (FBR) algorithm. We tested this on a 30-image stack of Sentinel-1 data over a region with different environments and a fair appearing on a
Michenot, Florent, Guinvarc'H, Régis, Thirion-Lefevre, Laetitia   +2 more
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Intercontinental trends in functional and phylogenetic structure of stream fish assemblages

Ecology and Evolution, 2019
Understanding of community assembly has been improved by phylogenetic and trait‐based approaches, yet there is little consensus regarding the relative importance of alternative mechanisms and few studies have been done at large geographic and ...
Luke M. Bower, Kirk O. Winemiller
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Integrating Disturbance, Seasonality, Multi-Year Temporal Dynamics, and Dormancy Into the Dynamics and Conservation of Metacommunities

Frontiers in Ecology and Evolution, 2020
The metacommunity framework has rapidly become a dominant concept used by ecologists to understand community assembly. By emphasizing extinction-colonization dynamics, dispersal, and species’ niche requirements in determining community structure ...
Marcel Holyoak, Tal Caspi, Lauren W. Redosh   +2 more
doaj   +1 more source

Changes in Phylogenetic and Functional Diversity of Ciliates along the Course of a Mediterranean Karstic River

Microorganisms, 2022
Ciliates are a group of phagotrophic protists found in a wide variety of ecosystems. This study builds on recent studies of ciliates in the Krka river and investigates changes in the phylogenetic and functional diversity of ciliates in biofilm to predict
Vesna Gulin Beljak, Antonija Kulaš, Guillaume Lentendu, Barbara Vlaičević, Marija Gligora Udovič, Mirela Sertić Perić, Fran Rebrina, Petar Žutinić, Sandi Orlić, Renata Matoničkin Kepčija   +9 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source