Results 61 to 70 of about 71,585 (251)

Geography and Environmental Governance I: Governing with Environmental Data

Progress in Environmental Geography
New data technologies abound in environmental politics. It is promised that these technologies will make the task of managing human impacts on the environment faster, easier, and more rational. Geographers have been among those eyeing this turn critically, illuminating how new data technologies are performing new environmental entities and scales of ...
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Climate Change Will Aggravate South Asian Cropland Exposure to Drought by the Middle of 21st Century

Earth's Future
Drought has a paramount impact on global agriculture and food security. However, the study on future cropland areas that can incur drought is inadequate.
Sanjit Kumar Mondal, Buda Su, Jinlong Huang, Jianqing Zhai, Guojie Wang, Zbigniew W. Kundzewicz, Yanjun Wang, Shan Jiang, Han Jiang, Jian Zhou, Tong Jiang   +10 more
doaj   +1 more source

Environmental, Social, And Governance Disclosure on Firm Value: The Moderating Role of Profitability

Jurnal Akuntansi
Purpose – This study aims to empirically prove the positive influence of environmental, social, and governance disclosure on firm value in companies listed on the Indonesia Stock Exchange. In addition, this study also wants to empirically prove whether
Lina Lina, Nigel William Rinaldy
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Localization of SDGs through Disaggregation of KPIs

Economies, 2018
The United Nation’s Agenda 2030 and Sustainable Development Goals (SDGs) pick up where the Millennium Development Goals (MDGs) left off. The SDGs set forth a formidable task for the global community and international sustainable development over the next
Manohar Patole
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Health expenditure, governance and SDG3 nexus: a longitudinal analysis in BRICS economies

Globalization and Health
Background Achieving Sustainable Development Goal 3 (SDG3): good health and well-being, requires significant health investments and effective governance.
Md. Mominur Rahman, Tasneem Islam Dyuti, Mohammad Tareque, Mohammed Alnour   +3 more
doaj   +1 more source