Results 61 to 70 of about 820,522 (298)

Global environmental governance: the challenge of accountability [PDF]

open access: yes, 2010
This repository item contains a single issue of Sustainable Development Insights, a series of short policy essays that began publishing in 2008 by the Boston University Frederick S. Pardee Center for the Study of the Longer-Range Future. The series seeks
Halle, Mark, Najam, Adil
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The socioeconomic correlates of the willingness to conserve: contextualizing the conservation of the Mt. Magdiwata watershed forest reserve in San Francisco, Agusan del Sur, Philippines

open access: yesHumanities & Social Sciences Communications
Mt. Magdiwata was declared a watershed and forest reserve in the 1990s to protect it from threats posed by agriculture, mining, and other human activities. This study examined the socioeconomic correlates of local residents’ willingness to participate in
Raquel Balanay   +4 more
doaj   +1 more source

EUROPEAN VALUES IN ENVIRONMENTAL GOVERNANCE OF THE EASTERN PARTNERSHIP COUNTRIES

open access: yesМіжнародні відносини: теоретико-практичні аспекти, 2018
Main objective of the study is the analysis of the environmental governance in the Eastern Partnership countries. Methodology of the study includes an analysis of the European Union and the countries of the Eastern Partnership documents devoted to the ...
Tetiana Perha
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Global fisheries governance and case study of fisheries governance of Autonomous Region of European Union – Azores [PDF]

open access: yes, 2014
This article seeks to identify the key principles that should guide the definition of the Global Fisheries Governance and Management. A particular focus for this work has been the concept of participative governance and the co-management systems in which
Paramio, Luz, Tomkova, Katerina
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Mapping municipal food supply: A longitudinal‐spatial case study in Southern Germany

open access: yesUrban Agriculture & Regional Food Systems
German food supply structures show heavy market concentration, which is often framed as a result of economies of scale and scope, individual purchasing behavior, and restrictive EU regulations.
Elena Mager   +3 more
doaj   +1 more source

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