FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Environmental Justice and Roma Communities in Central and Eastern Europe [PDF]
, 2009 This is the pre-peer-reviewed version of the following article: Harper, Krista, Tamara Steger, and Richard Filcak. 2009. Environmental Justice and Roma Communities in Central and Eastern Europe.
Steger, Tamara +2 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Evaluation Of Environmental Governance: The Case Of Trabzon Metropolitan Municipality
Siyasal: Journal of Political SciencesTackling environmental problems that transcend political boundaries requires coordinated global and local action. Environmental governance is a tool for achieving coordination to deal with environmental problems worldwide. In the process of environmental
Emrah Firidin +1 more
doaj +1 more source
Von Environmental Governance zu Landscape Governance: Multi-Level-Governance und Politics of Scale [PDF]
Governance has definitely become a very iridescent concept in recent years. The term is widely used, meanwhile, in almost all social-science disciplines as well as in the political process.
Görg, Christoph
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Between the sun and us: Expert perceptions on the innovation, policy, and deep uncertainties of space-based solar geoengineering [PDF]
, 2022 Space-based geoengineering is gaining attention, if not necessarily traction, as a possible “break the glass” solution to mitigate the worst impacts of climate change and facilitate the transition to a low-carbon future.
Sovacool, Benjamin K +4 more
core
The Relationship of Carbon Emission Disclosure on The Cost of Debt
SAGE OpenCarbon Emission Disclosure (CED) trends have been positive for several years. Unfortunately, studies focusing on the relationship between CED and the Cost of Debt (COD) still need to be made available, particularly in emerging countries.
Mohammad Nasih +4 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Relationship Between Corporate Governance And Environmental Disclosure: UK Evidence [PDF]
, 2012 The increasing global concern for the environment, the demand for increased stakeholder reporting, and the importance of sound corporate governance structures have triggered the need for more research into the value creation of environmental disclosure ...
ABURAYA, RANIA,KAMAL +1 more
core