Results 81 to 90 of about 148,517 (308)
The method of settling environmental conflicts in Indonesia: Alternative dispute resolution [PDF]
E3S Web of ConferencesRapid progress poses significant dangers to environmental contamination and harm, leading to disruptions in the conservation of the local ecosystem. Damage to the environment and pollution represent a collective responsibility shouldered by society, with
Sari Rafiqa +2 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Landscapes of harm: Environmental crime and the passive witness in children’s graphic narratives
EncyclopaideiaUnlike traditional narratives that follow crime-solution-restoration patterns, environmental crime manifests as pervasive, ongoing, and unresolvable conditions that saturate landscapes and lived experience.
Chang Hasheminezhad-Li
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Possible preferences and the harm of existence
, 2009 How good or bad is a person’s life? How good or bad is a world? In this dissertation, I will attempt to answer these questions. Common-sense would dictate that if a person’s life would be extremely bad, then bringing her into existence is a bad thing.
Larock, Marc
core
How Perceived Exposure to Environmental Harm Influences Environmental Behavior in Urban China
, 2013 Rapid environmental degradation in China makes understanding how perceived exposure to environmental harm influences environmental attitudes and participation in pro-environmental behaviors among the Chinese people crucial.
Chen, Xiaodong +5 more
core +1 more source
Environmental Harm Resulting from Israeli Bombing of Gaza: Legal Aspects
Arab Studies QuarterlyIsrael’s unprecedented bombardment of the Gaza Strip has caused more than 100,000 casualties and the forced displacement of most of Gaza’s 2.3 million inhabitants, but there is a “silent victim”: the environment, which includes the natural and built ...
Joni Aasi
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source