Results 141 to 150 of about 14,325,844 (399)

Educação em saúde e educação ambiental: uma experiência integradora

open access: yesCadernos de Saúde Pública
Este texto relata um trabalho com professores do ensino básico de alguns municípios brasileiros com diferentes perfis: do litoral ao interior, de capitais a cidades pequenas.
Danielle Grynszpan
doaj  

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Health and Environmental Incentives of Adopted Ecological Technologyin Rice Farming Insentif Kesehatan Dan Lingkungan Dari Teknologi Ekologi Yang Diserap Pada USAhatani Padi [PDF]

open access: yes, 2005
Selama kurun waktu 1970-80an, pertanian Indonesia terlihat tidak berkelanjutan karena penerapan teknologi berbasis teknologi kimiawi, yang merusak kesehatan dan lingkungan.
Mariyono, J. (Joko)
core  

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Protecting public health during drought conditions [PDF]

open access: yes
"In April 2008, CDC, the American Water Works Association (AWWA), the National Oceanic and Atmospheric Administration (NOAA), and the U.S. Environmental Protection Agency (EPA) committed to collaboratively creating a guide for public health and other ...
National Center for Environmental Health (U.S.)
core  

III. Evaluation of Environmental Health Programs

open access: green, 1959
P. W. Purdom   +2 more
openalex   +2 more sources

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

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