Results 141 to 150 of about 4,497,175 (353)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

The National Nanotechnology Initiative Approach to Environment, Health, and Safety: A Model for Future Science Investments

Federal History, 2016
This article discusses the very recent story about the new science of nanotechnology and the careful and clear-headed efforts to regulate it. Nanotechnology offers great promise in numerous applications, including national security, but can also raise ...
Brandi L. Schottel, Barbara Karn
doaj  

Administrative Decentralization of Environmental Health Programs

, 1960
J. W. R. Norton
openalex   +2 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

American Heart Association EPI|Lifestyle Scientific Sessions: 2022 Meeting Highlights

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Elisabeth L. P. Sattler, Oluwabunmi Ogungbe, Amelia S. Wallace, Zahra Aryan, Noelle Castilla‐Ojo, Jin Dai, Ileana De Anda‐Duran, Kathryn Foti, Charles A. German, Eric T. Hyde, Scott R. Jafarian‐Kerman, Karla N. Kendrick, Ben King, Adam Edward Lang, Olive Tang, Ruth‐Alma Turkson‐Ocran, Luis A. Rodriguez, Frances M. Wang, Mingyu Zhang, Marie‐France Hivert, Pamela L. Lutsey   +20 more
doaj   +1 more source

Environmental Health in Community Growth: An Administrative Guide to Metropolitan Area Sanitation Practices Committee, Engineering and Sanitarian Section, APHA

, 1963
Floyd B. Taylor, David B. Lee, Willis VanHeuvelen, I.G. Grossman, Herbert H. Hasson, H. Clifford Mitchell, Dixon R. Olive, Emanuel H. Pearl, Joseph W. Price, Ivan F. Shull, Warren Smith, Joseph A. Salvato   +11 more
openalex   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Citizen participation and environmental health action: the case of air pollution control.

, 1969
Nahum Z. Medalia
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Housing as an Environmental Factor in Mental Health: The Johns Hopkins Longitudinal Study

, 1960
Daniel M. Wilner, Rosabelle Price Walkley, John Schram, Thomas C. Pinkerton, Matthew Tayback   +4 more
openalex   +1 more source