Results 121 to 130 of about 2,135,040 (310)

Environmental health action in indigenous communities

open access: yes, 2001
This paper explores the ways in which a mismatch between research purpose and local outcomes can significantly undermine the credibility of Indigenous health staff within their communities.
Stephenson, Peter
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Environmental health practice : for today and for the future

open access: yes, 2001
In order to gain an insight into the changing role of the environmental health workforce, 40 in-depth, structured interviews were undertaken between July and September 2000.
Nicholson, Rosemary
core  

[Environmental health in Peru].

open access: yesRevista peruana de medicina experimental y salud publica, 2014
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Gustavo F. Gonzales, Kyle Steenland
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Environmental health nexus newsletter ; Volume 16, February 2023

open access: yes
CDC\u2019s Environmental Health Nexus (EH Nexus) shares environmental health messages with the public and gives special attention to environmental justice.EH Nexus newsletters provide information about environmental health issues and promotes actions to ...

core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Division of Environmental Hazards & Health Effects [PDF]

open access: yes
CDC\u2019s Division of Environmental Hazards & Health Effects (EHHE) focuses primarily on the following:\u2022 Air Pollution and Respiratory Health\u2022 Chemical and Radiologic Terrorism\u2022 Environmental Public Health Tracking\u2022 Health Studies ...

core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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