Results 101 to 110 of about 2,135,040 (310)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Achieving Environmental Health Equity : The Need and Opportunities for Public Health Action [PDF]

open access: yes
ENVIRONMENTAL HEALTH DISPARITIES are the result of current and historic systemic exclusion, disenfranchisement and disinvestment of specific communities and individuals in the U.S.

core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Ten essential environmental public health services

open access: yes
These 10 essential environmental public health services identify the actions necessary to the protection and improvement of environmental public health. They are adapted from the 10 essential public health services and the core functions of public health.

core  

Environmental Health and Safety: Annual Report 2015

open access: yes, 2014
The University of Texas at Austin Environmental Health and Safety provides a summary report annually.
UT Environmental Health and Safety
core   +1 more source

Response of Hard-Bottom Macro-Zoobenthos to the Transition of a Mediterranean Mariculture Fish Plant (Mar Grande of Taranto, Ionian Sea) into an Integrated Multi-Trophic Aquaculture (IMTA) System

open access: yesJournal of Marine Science and Engineering
This study investigates the effects on hard-bottom macro-zoobenthic communities of converting a mariculture plant into an Integrated Multi-Trophic Aquaculture (IMTA) system. This study was conducted from 2018 to 2021 in the semi-enclosed Mar Grande basin
Roberta Trani   +7 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Long-Term Effect of Air Pollution on COPD Exacerbations: AIREPOC Cohort in Bogotá, Colombia

open access: yesAtmosphere
(1) Background: Evidence on the association between air pollution and the risk of exacerbations of chronic obstructive pulmonary disease (COPD) is scarce and inconsistent.
Astrid Berena Herrera López   +8 more
doaj   +1 more source

Environmental Health [PDF]

open access: yesAmerican Journal of Public Health, 1972
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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