Results 91 to 100 of about 2,135,040 (310)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Workgroup Report: Developing Environmental Health Indicators for European Children: World Health Organization Working Group

open access: yes, 2007
A working group coordinated by the World Health Organization developed a set of indicators to protect children’s health from environmental risks and to support current and future European policy needs.
Kathy Pond   +23 more
core   +1 more source

Occupational Exposure to Volatile Organic Compounds in Polyurethane Foam Production—Concentration, Variability and Health Risk Assessment

open access: yesMolecules
Volatile organic compounds (VOCs) are a major occupational concern in polyurethane foam production, where exposure may impact worker health. This study identified key VOCs and evaluated their concentrations across different sections of a polyurethane ...
Andrzej R. Reindl   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

CDC's Division of Environmental Health Science and Practice [PDF]

open access: yes
CDC\u2019s Division of Environmental Health Science and Practice (DEHSP) works to protect the health and quality of life of all people in the United States.

core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Carcinogenic contaminants in groundwater in the Ebocha and Mgbede oil fields of Southern Nigeria

open access: yesRUDN Journal of Ecology and Life Safety
In accordance with the purpose and objectives of this study, standard methods were applied with the aim and objectives of this study, standard methods were applied in evaluating groundwater contamination from an oil waste pit in the Mgbede and Ebocha Oil
Mazico Henry Ikwulemenze   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Environmental public health performance standards (Version 2.0) [PDF]

open access: yes
Environmental health programs can use the Environmental Public Health Performance Standards (EnvPHPS) to improve environmental health services delivered in their community This document provides background information on the standards and instructions ...

core  

Building Interdisciplinary Partnerships for Community-Engaged Environmental Health Research in Appalachian Virginia

open access: yes, 2020
This article describes a collaboration among a group of university faculty, undergraduate students, local governments, local residents, and U.S. Army staff to address long-standing concerns about the environmental health effects of an Army ammunition ...
Lauren Buttling   +15 more
core   +1 more source

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