Results 91 to 100 of about 4,747,291 (301)

Identification and Prioritization of Strategies for Removing Pharmaceutical Contaminants from Hospital Wastewater in Selected Hospitals of Markazi Province Using the Analytic Hierarchy Process (AHP) [PDF]

بیمارستان
Background and purpose: Pharmaceutical pollutants in hospital wastewater pose significant environmental and public health risks. This study aimed to identify and prioritize effective strategies for removing these contaminants from the wastewater of ...
Abbas Jahangiri
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Air Pollution, Socioeconomic Status, and Avoidable Hospitalizations: A Multifaceted Analysis

Mathematical and Computational Applications
This study investigates the combined effects of air pollution and socioeconomic factors on disease incidence and severity, addressing gaps in prior research that often analyzed these factors separately.
Carlos Minutti-Martinez, Miguel F. Mata-Rivera, Magali Arellano-Vazquez, Boris Escalante-Ramírez, Jimena Olveres   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Occupational Exposure to Volatile Organic Compounds in Polyurethane Foam Production—Concentration, Variability and Health Risk Assessment

Molecules
Volatile organic compounds (VOCs) are a major occupational concern in polyurethane foam production, where exposure may impact worker health. This study identified key VOCs and evaluated their concentrations across different sections of a polyurethane ...
Andrzej R. Reindl, Ewa Olkowska, Jakub Pawłowski, Lidia Wolska   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Urban air pollution and health inequities: a workshop report. [PDF]

, 2001
Over the past three decades, an array of legislation with attendant regulations has been implemented to enhance the quality of the environment and thereby improve the public's health.
American Lung Association
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Carcinogenic contaminants in groundwater in the Ebocha and Mgbede oil fields of Southern Nigeria

RUDN Journal of Ecology and Life Safety
In accordance with the purpose and objectives of this study, standard methods were applied with the aim and objectives of this study, standard methods were applied in evaluating groundwater contamination from an oil waste pit in the Mgbede and Ebocha Oil
Mazico Henry Ikwulemenze, Ifeanyichukwu Clinton Ezekwe, Enos Ihediohamma Emereibeole, Leonard Udochi Mgbeahuruike, Joseph Ikechukwu Nwachukwu   +4 more
doaj   +1 more source

Leveraging Epidemiology to Improve Risk Assessment. [PDF]

, 2011
The field of environmental public health is at an important crossroad. Our current biomonitoring efforts document widespread exposure to a host of chemicals for which toxicity information is lacking.
Burke, Thomas A, Fox, Mary A, Nachman, Keeve E, Rodricks, Joseph V, Sheehan, Mary C, Woodruff, Tracey J   +5 more
core