Results 81 to 90 of about 29,397,810 (306)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Introduction: Located in Mpumalanga’s Highveld Priority Area (HPA), Nkangala and Gert Sibande are well‑known for sustained exposure to high levels of air pollution, which is linked to adverse health effects.
Danielle A Millar +5 more
doaj +1 more source
From Crowdsourcing to Extreme Citizen Science: Participatory Research for Environmental Health.
Environmental health issues are becoming more challenging, and addressing them requires new approaches to research design and decision-making processes.
Paul English +2 more
semanticscholar +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Impact of Green Building Implementation on Health and Well-being of Building Users in Indonesia
This research conducts a systematic literature review, adopting the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, to examine the impact of green building implementation on health and well-being of users in Indonesia.
Lendra Lendra +2 more
doaj +1 more source
Environmental health literacy (EHL) is a relatively new framework for conceptualizing how people understand and use information about potentially harmful environmental exposures and their influence on health.
K. Gray
semanticscholar +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Climate change has become a global health emergency in recent decades, with far-reaching effects on neurological and psychiatric health; however, their relationship remains poorly understood.
Pablo S. Martínez Lozada +1 more
doaj +1 more source
BackgroundPolicy and decision-making processes are routinely challenged by the complex and dynamic nature of environmental health problems. System dynamics modelling has demonstrated considerable value across a number of different fields to help decision-
D. Currie, Carl S. Smith, P. Jagals
semanticscholar +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

