Results 81 to 90 of about 29,397,810 (306)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Human Health Risk Assessment of PM2.5, NO2, and SO2 and its Impact on Mortality in Nkangala and Gert Sibande, South Africa

open access: yesAnnals of Global Health
Introduction: Located in Mpumalanga’s Highveld Priority Area (HPA), Nkangala and Gert Sibande are well‑known for sustained exposure to high levels of air pollution, which is linked to adverse health effects.
Danielle A Millar   +5 more
doaj   +1 more source

From Crowdsourcing to Extreme Citizen Science: Participatory Research for Environmental Health.

open access: yesAnnual Review of Public Health, 2018
Environmental health issues are becoming more challenging, and addressing them requires new approaches to research design and decision-making processes.
Paul English   +2 more
semanticscholar   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Impact of Green Building Implementation on Health and Well-being of Building Users in Indonesia

open access: yesJurnal Presipitasi
This research conducts a systematic literature review, adopting the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, to examine the impact of green building implementation on health and well-being of users in Indonesia.
Lendra Lendra   +2 more
doaj   +1 more source

From Content Knowledge to Community Change: A Review of Representations of Environmental Health Literacy

open access: yesInternational Journal of Environmental Research and Public Health, 2018
Environmental health literacy (EHL) is a relatively new framework for conceptualizing how people understand and use information about potentially harmful environmental exposures and their influence on health.
K. Gray
semanticscholar   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Neurological and mental health in the era of climate change: mechanisms, clinical impacts, and adaptation

open access: yesFrontiers in Public Health
Climate change has become a global health emergency in recent decades, with far-reaching effects on neurological and psychiatric health; however, their relationship remains poorly understood.
Pablo S. Martínez Lozada   +1 more
doaj   +1 more source

The application of system dynamics modelling to environmental health decision-making and policy - a scoping review

open access: yesBMC Public Health, 2018
BackgroundPolicy and decision-making processes are routinely challenged by the complex and dynamic nature of environmental health problems. System dynamics modelling has demonstrated considerable value across a number of different fields to help decision-
D. Currie, Carl S. Smith, P. Jagals
semanticscholar   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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