Results 141 to 150 of about 29,397,810 (306)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Environmental health practice : for today and for the future

open access: yes, 2001
In order to gain an insight into the changing role of the environmental health workforce, 40 in-depth, structured interviews were undertaken between July and September 2000.
Nicholson, Rosemary
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Environmental health action in indigenous communities

open access: yes, 2001
This paper explores the ways in which a mismatch between research purpose and local outcomes can significantly undermine the credibility of Indigenous health staff within their communities.
Stephenson, Peter
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Environmental health nexus newsletter ; Volume 16, February 2023

open access: yes
CDC\u2019s Environmental Health Nexus (EH Nexus) shares environmental health messages with the public and gives special attention to environmental justice.EH Nexus newsletters provide information about environmental health issues and promotes actions to ...

core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Environmental Public Health Performance Standards Assessment Toolkit

open access: yes
This EnvPHPS Assessment Toolkit provides tools that can help facilitate the process of preparing, conducting, and following up on your assessment.The Environmental Public Health Performance Standards (EnvPHPS) are a set of 27 standards modeled after the ...

core  

Division of Environmental Hazards & Health Effects [PDF]

open access: yes
CDC\u2019s Division of Environmental Hazards & Health Effects (EHHE) focuses primarily on the following:\u2022 Air Pollution and Respiratory Health\u2022 Chemical and Radiologic Terrorism\u2022 Environmental Public Health Tracking\u2022 Health Studies ...

core  

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