Results 131 to 140 of about 2,135,040 (310)

Environmental Public Health Performance Standards Assessment Toolkit

open access: yes
This EnvPHPS Assessment Toolkit provides tools that can help facilitate the process of preparing, conducting, and following up on your assessment.The Environmental Public Health Performance Standards (EnvPHPS) are a set of 27 standards modeled after the ...

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The Value of Environmental Health Services : Exploring the Evidence [PDF]

open access: yes
As a core public health discipline, environmental health interventions fundamentally focus on preventing disease and creating healthy, supportive environments.

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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

National Center for Environmental Health at the turn of the century, 1999-2003 [PDF]

open access: yes
The National Center for Environmental Health (NCEH), as part of the Centers for Disease Control and Prevention (CDC), is unique in the federal government for its focus on public health issues related to the environment.

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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Environmental health 2000. [PDF]

open access: yesEnvironmental Health Perspectives, 1998
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Environmental public health tracking program; closing America's environmental public health gap, 2003 [PDF]

open access: yes
"Environmental public health tracking is the ongoing collection, integration, analysis, and interpretation of data about environmental hazards, exposure to environ mental hazards, and human health effects potentially related to exposure to environmental ...

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