Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Scale Dependence of Woody Plant β‐Diversity in a Tropical Rainforest Metacommunity
β‐diversity is a central concept to understanding community assembly, yet how its decomposition components and underlying drivers vary with spatial extent remains insufficiently understood.
Jie Yao +8 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
A study of heterogeneity of environmental variance for slaughter weight in pigs
This work presents an analysis of heterogeneity of environmental variance for slaughter weight (175 days) in pigs. This heterogeneity is associated with systematic and additive genetic effects. The model also postulates the presence of additive genetic effects affecting the mean and environmental variance.
Ibánez-Escriche, N +3 more
openaire +4 more sources
Environmental Kuznets Curves for CO2: Heterogeneity Versus Homogeneity [PDF]
We explore the emissions income relationship for CO2 in OECD countries using various modelling strategies.Even for this relatively homogeneous sample, we find that the inverted-U-shaped curve is quite sensitive to the degree of heterogeneity included in ...
Dijkgraaf, E. +2 more
core
Efficiency Effects of Quality of Service and Environmental Factors: Experience from Norwegian Electricity Distribution [PDF]
Since the 1990s, efficiency and benchmarking analysis has increasingly been used in network utilities research and regulation. A recurrent concern is the effect of environmental factors that are beyond the influence of firms (observable heterogeneity ...
Growitsch, Christian +2 more
core +3 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Terminology and quantification of environmental heterogeneity in species‐richness research
ABSTRACTSpatial environmental heterogeneity (EH) is an important driver of species diversity, and its influence on species richness has been analysed for numerous taxa, in diverse ecological settings, and over a large range of spatial scales. The variety and ambiguity of concepts and terminology, however, have hampered comparisons among studies.
Anke Stein, Holger Kreft
openaire +3 more sources
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Bird communities in two fragments of Cerrado in Itirapina, Brazil
The Cerrado domain is a mosaic of vegetation types at the local scale, and this environmental heterogeneity leads to high regional bird diversity. Therefore, we aimed to survey quantitative and qualitatively the bird fauna of two fragments of Cerrado and
M. Telles, MM. Dias
doaj +1 more source

