Results 81 to 90 of about 362,096 (260)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A study of heterogeneity of environmental variance for slaughter weight in pigs
Animal, 2008 This work presents an analysis of heterogeneity of environmental variance for slaughter weight (175 days) in pigs. This heterogeneity is associated with systematic and additive genetic effects. The model also postulates the presence of additive genetic effects affecting the mean and environmental variance.
Ibánez-Escriche, N +3 more
openaire +4 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Predicting local adaptation in fragmented plant populations: implications for restoration genetics
Evolutionary Applications, 2012 Understanding patterns and correlates of local adaptation in heterogeneous landscapes can provide important information in the selection of appropriate seed sources for restoration.
Melinda Pickup +3 more
doaj +1 more source
Diet heterogeneity and antioxidant defence in Barn Swallow Hirundo rustica nestlings
Avocetta, 2019 Populations of several farmland bird species have suffered sharp declines linked to increased environmental homogeneity and reduced biodiversity, particularly of insects, upon which several farmland birds feed.
Camila Paola Grigolo +7 more
doaj +1 more source
Terminology and quantification of environmental heterogeneity in species‐richness research
Biological Reviews, 2014 ABSTRACTSpatial environmental heterogeneity (EH) is an important driver of species diversity, and its influence on species richness has been analysed for numerous taxa, in diverse ecological settings, and over a large range of spatial scales. The variety and ambiguity of concepts and terminology, however, have hampered comparisons among studies.
Anke Stein, Holger Kreft
openaire +3 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
BiologyIntra-individual variation in floral traits is linked to plant fitness, playing a central role in sexual selection. This variation can arise from architectural constraints, such as flower position on the inflorescence axis, and from environmental factors.
Guilherme Ramos Demetrio +2 more
doaj +1 more source
Seasonal and habitat structure of an anuran assemblage in a semideciduous forest area in Southeast Brazil [PDF]
Anais da Academia Brasileira de CiênciasIn this study, we evaluated the reproductive activity and the temporal and spatial distributions of anuran assemblages in three environments within a semideciduous forest in Southeast Brazil, located at Municipality of Barão de Monte Alto, State of Minas
ELVIS A. PEREIRA +4 more
doaj +2 more sources